The Effect of Non-Thermal Microwave-Treated Physiological Solution on Isolated Heart Muscle of Snail

The effects of non-thermal intensity of microwave (NT MW)- treated physiological solutions (PS) on muscle contractility, 45Ca uptake by muscle and muscle hydration of snail isolated heart in normal and K+-free PS were studied. The intra-cordial perfusion by NT MW-treated PS led to inhibition of heart beating with gradual decrease of the amplitudes of muscle contraction, the weakness of the Na+/K+ pump-induced transient inhibition of heart beating (TIHB), the inhibition of 45Ca2+ uptake by muscle, the increase of intracellular cGMP contents and muscle dehydration. The obtained data serve as additional evidence for hypothesis that cell bathing aqua solution is a primary target for non-thermal effect of MW on cells and organisms.