Current Biomarkers (Discontinued) - Volume 7, Issue 1, 2017

The psoriatic disease has a multi-factorial determinism being generated by a complex array of genetic, immunologic, and environmental factors. In this array, cellular interplay takes place maintaining the epidermal equilibrium. Psoriasis pathophysiology is characterized by keratinocytes hyperproliferation and immune cell infiltration in the dermis and epidermis. Innate and adaptive immune cells are highly involved, the m Read More

Background: Canine parvovirus (CPV) enteritis is an important cause of high morbidity and mortality in pups. The high incidence of parvoviral enteritis is due to high capability of CPV to evolve into more virulent and resistant variants. The condition may be worsening in case of local gastrointestinal and systemic inflammation. In addition to CPV enteritis less common is the cardiac form, which attacks the heart muscle Read More

Background: Cancer is one of the most deadly diseases in the world. Cervical cancer is the second most common cancer in women worldwide. The major cause of cervical cancer has been found to be the infection with Human Papillomavirus (HPV). Out of over 100 types of HPV, the two types, which are considered high-risk HPV types, are HPV-16 and HPV-18. Several vaccines are available commercially which comprise Cervari Read More

Background: The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis are a heterogeneous group of autoimmune diseases that predominantly affects small vessels. Churg Strauss Syndrom (CSS), Wegener's Granulomatosis (WG) and Microscopic polyangiitis (MPA) are the three clinical entities associated to this group. Marked eosinophilia, pulmonary involvement associated with dense eosinophilic infiltration Read More

Background: Epstein Barr Virus (EBV) infection has been associated with the Rheumatoid Arthritis (RA) etiopathology, thus, considering it a relevant etiological agent in the disease development. We have previously observed the Hyaluronic Acid (HA) serum increase in active RA patients (DAS 28-4 > 2.6) which might be responsible for the erythrocyte deformability, estimated by the erythrocyte Rigidity Index (RI). Objective: In the pr Read More

Background: Celery (Apium graveolens L.) is considered one of the most important cash crops of Apiaceae family. However, due to minimal genetic and genomic resources, most of the past studies were based on physiological and biochemical analysis rather than molecular breeding. Objective: The present in silico molecular study is an attempt to develop dbEST derived simple sequence repeats in celery. Method: Implementatio Read More