Cancer and Aids: New Trends in Drug Design and Chemotherapy

Carlton Anthony Taft; Carlos Henrique Tomich de Paula da Silva

doi:10.2174/157340906778226382

ISSN: 1573-4099
E-ISSN: 1875-6697

Cancer and Aids: New Trends in Drug Design and Chemotherapy
Authors: Carlton Anthony Taft¹ and Carlos Henrique Tomich de Paula da Silva²
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Affiliations: ¹ Centro Brasileiro de Pesquisas Fisicas, Rua Dr. Xavier Sigaud, 150, CEP, 22290-180, Rio de Janeiro, RJ, Brazil. ² Centro Brasileiro de Pesquisas Fisicas, Rua Dr. Xavier Sigaud, 150, CEP, 22290-180, Rio de Janeiro, RJ, Brazil.
Source: Current Computer - Aided Drug Design, Volume 2, Issue 3, Sep 2006, p. 307 - 324
DOI: https://doi.org/10.2174/157340906778226382
- Available online: 01 Sep 2006

Abstract

We present a comprehensive but not exhaustive review of new trends in drug discovery and targets for cancer and AIDS which begins by highlighting the different historical stages of drug discovery from clinical diagnosis, natural compounds, serendipity and chemotherapy to the present age of modern experimental and computational techniques. The current state of the art of computer-aided drug design and selected recent applications to Cancer and AIDS are discussed. Novel targets and drugs in Cancer and AIDS are analyzed. In conclusion, future perspectives for drug discovery, design and therapeutics in cancer and AIDS are presented.

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2006-09-01

2025-01-18

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Article Type: Research Article

Keyword(s): anti-VEGF antibody; chemokine co-receptors; HIV-1; molecular modeling (MM); non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Cancer and Aids: New Trends in Drug Design and Chemotherapy

Abstract

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