Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review

Colin S. Creaser; Lucy Ratcliffe

doi:10.2174/157341106775197420

ISSN: 1573-4110
E-ISSN: 1875-6727

Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review
Authors: Colin S. Creaser¹ and Lucy Ratcliffe²
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¹ School of Biomedical and Natural Sciences, Interdisciplinary Biomedical Research Centre, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK; ² School of Biomedical and Natural Sciences, Interdisciplinary Biomedical Research Centre, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK;
Source: Current Analytical Chemistry, Volume 2, Issue 1, Jan 2006, p. 9 - 15
DOI: https://doi.org/10.2174/157341106775197420
- Available online: 01 Jan 2006

Abstract

Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of APMALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.

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2006-01-01

2025-06-15

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Article Type: Research Article

Keyword(s): Atmospheric pressure; MALDI; Mass spectrometry

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Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review

Abstract

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