Electrochemical Biosensors for Superoxide Anion

Yang Tian; Lanqun Mao; Takeo Ohsaka

doi:10.2174/157341106775197376

ISSN: 1573-4110
E-ISSN: 1875-6727

Electrochemical Biosensors for Superoxide Anion
Authors: Yang Tian¹, Lanqun Mao² and Takeo Ohsaka³
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¹ Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226- 8502, Japan; ² Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226- 8502, Japan; ³ Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226- 8502, Japan;
Source: Current Analytical Chemistry, Volume 2, Issue 1, Jan 2006, p. 51 - 58
DOI: https://doi.org/10.2174/157341106775197376
- Available online: 01 Jan 2006

Abstract

The determination of superoxide anion (O2 .-) is of great physiological and pathological importance since O2 .- is considered to be involved in the etiology of aging, cancer, and progressive neurodegenerative diseases such as Parkinson's disease. The determination of the local concentration of O2 .- has been a relatively challenging analytical problem because of the low concentration, high reactivity and short lifetime of O2 .- in biological systems. This review raises a number of methods, highlighting electrochemical methodologies, for the determination of O2 .-. These electrochemical sensors and biosensors and their analytical characteristics are discussed in detail.

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2006-01-01

2025-05-09

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Article Type: Research Article

Keyword(s): Cytochrome c; Electrochemical biosensors; in vivo; Self-assembled monolayer (SAM); Superoxide anion (O2); Superoxide dismutase (SOD)

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Electrochemical Biosensors for Superoxide Anion

Abstract

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