A Review on Electrochemical Sensing of Cancer Biomarkers Based on Nanomaterial - Modified Systems

Diagnosis of cancer in the early stages can help treat efficiently and reduce cancerrelated death. Cancer biomarkers can respond to the presence of cancer in body fluids before the appearance of any other symptoms of cancer. The integration of nanomaterials into biosensors as electrochemical platforms offer rapid, sensitive detection for cancer biomarkers. The use of surface- modified electrodes by carbon nanomaterials and metal nanoparticles enhances the performance of electrochemical analysis in biosensing systems through the increase of bioreceptors loading capacity on the surface. In this review, novel approaches based on nanomaterial-modified systems in the point of care diagnostics are highlighted.