Applied Clinical Research, Clinical Trials and Regulatory Affairs - Volume 6, Issue 2, 2019

Background: Probiotics is a broad term used for friendly bacteria which are increasingly used in present scenario due to their wide range of health benefits accompanied by low cost and negligible side effects. The status of the probiotics as a component of food is not clear in the health industry. The use of probiotic bacteria is exploited over-the-counter as dietary supplements or in food products such as yogurt, as well as in the p Read More

Background: Pharmaceutical excipients are critical in the formulation of any dosage form. Not many additives employed in the drug product manufacture have properties, which meet the desired qualities that the finished product must have. Therefore, it is mandatory to mix the drug substance with other substances to overcome the deficiencies. As a result, almost all pharmaceutical products are mixtures of active ph Read More

Background: In pharmaceutical terms, quality means a product free from any contamination and delivers the therapeutic benefit specified in the label at a reproducible rate which can be assessed by carrying out in vivo or in vitro tests for evaluation of performance. Quality by Design (QbD) is a necessary tool in pharmaceutical environment for having product/process/method impregnated with quality. QbD is a move toward dr Read More

Introduction: Many physicians may be unfamiliar with the importance of hyaluronic acid (HA) and its physiological and biochemical functions at cellular level. Despite the vast number of published studies using HA in medical treatments, it is still difficult for the reader to clearly distinguish the different types of HA employed in different medical applications. In addition, published studies do not mention the exact type of HA used Read More