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2000
Volume 23, Issue 8
  • ISSN: 1871-5206
  • E-ISSN: 1875-5992

Abstract

This application describes the synthesis of new 1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione derivatives and methods of using these compounds as KRAS covalent inhibitors. This class of compounds is useful for treating cancer and other diseases associated with KRAS activity.

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/content/journals/acamc/10.2174/1871520623666221128110638
2023-05-01
2025-03-15
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/content/journals/acamc/10.2174/1871520623666221128110638
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  • Article Type:
    Editorial
Keyword(s): bicyclic dione compounds; cancer; covalent inhibitor; HRAS; KRAS mutant; NRAS
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