Skip to content
2000
Volume 21, Issue 8
  • ISSN: 1871-5206
  • E-ISSN: 1875-5992

Abstract

In the last 20 years, N-Heterocyclic Carbene (NHC) ligands have been ubiquitous in biological and medicinal chemistry. Part of their success lies in the tremendous number of topologies that can be synthesized and thus finely tuned that have been described so far. This is particularly true in the case of those derivatives, including fluorine or fluorinated fragments on their NHC moieties, gaining much attention due to their enhanced biological properties and turning them into excellent candidates for the development of novel metallodrugs. Thus, this review summarizes the development that fluorinated-NHC transition metal complexes have had and their impact on cancer treatment.

Loading

Article metrics loading...

/content/journals/acamc/10.2174/1871520620666200908103452
2021-05-01
2025-04-23
Loading full text...

Full text loading...

/content/journals/acamc/10.2174/1871520620666200908103452
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test