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- ISSN: 1871-5206
- E-ISSN: 1875-5992
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Immunogenicity, Immunopathogenicity, and Immunotolerance in One Graph
- Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), Volume 15, Issue 10, Dec 2015, p. 1264 - 1268
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- 01 Dec 2015
Abstract
The concept according to which unique, rare and common sequences may define immunogenicity, immunopathogenicity and immunotolerance, respectively, is graphically illustrated using a melanoma-associatedantigen, Melan-A/Mart-1, as a model. The final picture is consolidated by experimentally validated data from the scientific literature and may represent a concrete prelude to effective immunotherapies exempt from collateral autoimmune reactions.
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