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2000
Volume 13, Issue 10
  • ISSN: 1871-5206
  • E-ISSN: 1875-5992

Abstract

Twenty six compounds (coumarins, flavonoids and alkaloids) were evaluated for their ability to inhibit the growth of three human tumor cell lines: breast adenocarcinoma (MCF-7), non-small cell lung cancer (NCI-H460) and melanoma (A375-C5). Three of them [3-hydroxyflavone (6), 2’-hydroxy-3,4,4’,5,6’-pentamethoxychalcone (11), Siderin (20)] were very potent in inhibiting all human tumor cell lines tested. The structure / activity relationship is discussed.

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/content/journals/acamc/10.2174/1871520613666131125122857
2013-12-01
2025-07-06
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/content/journals/acamc/10.2174/1871520613666131125122857
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  • Article Type:
    Research Article
Keyword(s): Alkaloids; coumarins; flavonoids; tumor cell lines growth inhibitor
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