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- ISSN: 1871-5206
- E-ISSN: 1875-5992
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Antimitotic Chalcones and Related Compounds as Inhibitors of Tubulin Assembly
- Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), Volume 9, Issue 3, Mar 2009, p. 336 - 347
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- 01 Mar 2009
Abstract
The development of chalcones as antimitotic agents has led to the design of other analogues able to interact with tubulin and inhibit its assembly into microtubules. This activity has also been associated with their anti-vascular activity. This review focuses on the development of chalcones and related analogues as antimitotic agents.
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