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  3. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents)
  4. Volume 7, Issue 2
  5. Article
Volume 7, Issue 2
  • ISSN: 1871-5206
  • E-ISSN: 1875-5992

Abstract

This review highlights structural diversity of antimitotic agents. In particular, we emphasized current antimitotic therapies based on modulation of microtubule dynamics. With several successful anticancer drugs on the market and numerous compounds in clinical developments, tubulin-binding agents remain among the most important categories of anticancer agents. Compounds targeting mitotic kinases and kinesins are also discussed.

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/content/journals/acamc/10.2174/187152007780058650
2007-03-01
2025-04-01

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  • Article Type:     Research Article
Keyword(s): antimitotic agent; inhibitor of tubulin polymerization; microtubule-stabilizing agent; mitotic kinase; mitotic kinesin

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