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- ISSN: 1871-5206
- E-ISSN: 1875-5992
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The Synthesis and Use of Boronated Amino Acids for Boron Neutron Capture Therapy
- Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents), Volume 6, Issue 2, Mar 2006, p. 111 - 125
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- 01 Mar 2006
Abstract
The treatment of cancer remains one of the most challenging problems for humanity. Boron neutron capture therapy (BNCT) is a binary approach for cancer treatment that is particularly attractive in treating high-grade gliomas and metastatic brain tumors. Among types of boron-containing molecules used as BNCT agents, boronated amino acids have received significant attention for their preferentially uptake by growing tumor cells. This review emphasizes the synthesis of boronated amino acids.
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