Background: Malaria is still the deadliest parasitic disease caused by Plasmodium spp. Due to drug resistance and their unpleasant side effects of conventional researchers are enormously seeking to achieve antimalarial drugs with more curative effective less toxic and cost-affordable drugs using more advanced technology such as nanodrugs. Purpose: The present study aimed to examine the antimalarial effects of a novel synthesized nonochloro Read More

Background: Severe COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a kind of viral pneumonia induced by infection with the coronavirus that causes ARDS. It involves symptoms that are a combination of viral pneumonia and ARDS. Antiviral or immunosuppressive medicines are used to treat many COVID-19 patients. Several drugs are now undergoing clinical studies in order to see if they can be repurposed in the future. M Read More

Every year witnesses an outbreak of some or the other zoonotic disease that causes the unparalled loss of human life. The year 2022 presented the outbreak of Crimean Congo haemorrhagic fever (CCHF) which brought unprecedented challenges to individuals as well as to the healthcare system all around the world making it a serious health concern. Rising health concerns have highlighted the importance of managing and decreasing the further transmi Read More

Background: Sepsis is a major health problem worldwide and is associated with high morbidity and mortality with every hour delay in initiation of therapy. A conventional method of blood culture and Antimicrobial Susceptibility Testing (AST) takes around 48-72 hours. Empirical antibiotics need to be administered until the sensitivity report is made available. It has been estimated that 20-50% of the empirical antibiotics are inappropriate resulting in prolonge Read More

Coronavirus Disease-19 (COVID-19) is an infectious disease brought on by the extremely pathogenic and contagious severe acute respiratory syndrome-virus-2 (SARS-CoV-2). The agenda for the COVID-19 pandemic is dynamic and includes recent developments. Seven variants under monitoring (VUMs) one variant of interest (VOI) XBB.1.5 and their offspring lineages are currently being actively monitored by WHO. The VUMs are BA.2.75 CH.1.1 BQ.1 X Read More

Introduction: Currently the ongoing COVID-19 pandemic is posing a challenge to health systems worldwide. Unfortunately the true number of infections is underestimated due to the existence of a vast number of asymptomatic infected individual’s proportion. Detecting the actual number of COVID-19-affected patients is critical in order to treat and prevent it. Sampling of such populations so-called hidden or hard-to-reach populations is not possible using Read More

Background: The spectrum of the clinical features of coronavirus disease 2019 (COVID-19) spans from asymptomatic or mild disease to severe respiratory failure while different factors are related to its mortality rate. This research aimed to determine the clinical and laboratory characteristics and the associated factors of mortality in patients with COVID-19. Materials and Methods: Data were collected from hospitalized patients (May to June 2020) and COVI Read More

Nosocomial infections also known as healthcare-associated infections are a significant global concern due to their strong association with high mortality and morbidity in both developed and developing countries. These infections are caused by a variety of pathogens particularly the ESKAPE group of bacteria which includes the six pathogens Enterococcus faecium Staphylococcus aureus Klebsiella pneumoniae Acinetobacter baumannii Pseudomonas aerugino Read More