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- ISSN: 1570-1786
- E-ISSN:
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Synthesis of Oxepin-Annulated Quinolone Heterocycles by Ruthenium Catalyzed Enyne Bond Reorganization/Diels-Alder Reaction
- Source: Letters in Organic Chemistry, Volume 4, Issue 5, Jul 2007, p. 309 - 313
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- 01 Jul 2007
Abstract
Synthesis of oxepin-annulated quinolone heterocycles by the combination of Claisen rearrangement, the ringclosing metathesis and Diels-Alder reaction is described. The RCM or RCEM proceeded smoothly in the presence of Grubbs' first generation catalyst at room temperature under nitrogen atmosphere.
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