A Comprehensive Review on Current Perspectives of Flavonoids as Antimicrobial Agent

Flavonoids are the secondary plant metabolites with diversities of pharmacological activities like antioxidant, anticancer, anti-inflammatory, hepatoprotective, free radical scavenging activity and antiviral activities. Flavonoids have also been proved as a major contributor to an antimicrobial phytochemical. Being the major substituent of antibiotics, today flavonoids have attained great attention as there is an increase in the persistence of untreatable microbial infections due to microbial resistance. This review demonstrates the screening, isolation of extracts and derivatization of various flavonoids and their evaluation for antimicrobial potency. Recent advancements of various derivatives of flavonoids having antimicrobial activity have also been discussed in this review. This review helps researchers to get vast knowledge about flavonoids and also gives an idea for the current scenario of flavonoids and their applications as an antimicrobial agent.