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2000
Volume 21, Issue 28
  • ISSN: 1568-0266
  • E-ISSN: 1873-4294

Abstract

Imidazole has an important five-membered aromatic heterocyclic ring, which is available widely in natural products and synthetic molecules. The special structural characteristics of imidazole ring enable it to bind with a variety of enzymes and receptors through hydrogen bonds, coordination, ion-dipole and cation-π interactions, hydrophobic effects, and Van der Waals forces. These interactions promote several biological activities involving anti-tumor, anti-inflammatory, anti-microbial, and anti-viral properties. Herein, we review and discuss recent developments in using imidazole derivatives and their special pharmacological activities for the treatment of various diseases.

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/content/journals/ctmc/10.2174/1568026621666210527103225
2021-11-01
2025-07-07
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