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- ISSN: 1568-0266
- E-ISSN: 1873-4294
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Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes
- Source: Current Topics in Medicinal Chemistry, Volume 14, Issue 10, May 2014, p. 1271 - 1282
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- 01 May 2014
Abstract
This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.
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