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2000
Volume 11, Issue 18
  • ISSN: 1568-0266
  • E-ISSN: 1873-4294

Abstract

In the last twenty years a depth study on potential pharmaceutical applications of synthetic polymers at proteinlike structure as carrier for macromolecular prodrug production has been performed in academia and in industry. In particular α,β-poly(N-2-hydroxyethyl)-DL-aspartamide (PHEA), α,β-polyaspartylhydrazide (PAHy), poly(glutamic acid) (PGA), poly(aspartic acid) (PAA) and polylysine (PLL) have been extensively studied in this field. In the present review, the use of PHEA, PAHy, PGA as starting materials to prepare macromolecular prodrugs is reported and drug delivery and targeting aspects have been considered.

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/content/journals/ctmc/10.2174/156802611797183276
2011-09-01
2025-06-15
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/content/journals/ctmc/10.2174/156802611797183276
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