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Volume 11, Issue 15
  • ISSN: 1568-0266
  • E-ISSN: 1873-4294

Abstract

Thematic Analysis™ is a chemogenomic tool which has been developed and used to aid the process of GPCR drug discovery. This review covers the scientific rationale behind the development of this tool and provides examples of the successful application of the chemogenomic method in both hit finding and hit to lead stages of the drug discovery process.

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/content/journals/ctmc/10.2174/156802611796391302
2011-08-01
2024-11-19

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  • Article Type:     Research Article
Keyword(s): chemical scaffold; chemogenomic tool; Chemogenomics; drug discovery; focused libraries; GPCR; High Throughput Screening (HTS); library design; rational design of a focused library; selection of compounds from a diverse compound set; structure activity relationships (SAR); Thematic Analysis™; virtual screening

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