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2000
Volume 2, Issue 3
  • ISSN: 1568-0266
  • E-ISSN: 1873-4294

Abstract

Increasing insight into the genetics and molecular biology of cancer has resulted in the identification of an increasing number of potential molecular targets for anti-cancer drug discovery and development. These targets can be approached through exploitation of emerging structural biology,”rational“ drug design, screening of chemical libraries, or a combination of these methods. In this article we discuss the application of high-throughput screening to anti-cancer drug discovery, with special reference to approaches used at the U.S. National Cancer Institute.

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/content/journals/ctmc/10.2174/1568026023394317
2002-03-01
2024-11-24
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  • Article Type:
    Review Article
Keyword(s): (cat) assays; anticancer drug discovery; molecular medicine
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