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- ISSN: 1574-888X
- E-ISSN: 2212-3946
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Gli1+ Mesenchymal Stem Cells in Bone and Teeth
- Source: Current Stem Cell Research & Therapy, Volume 17, Issue 6, Aug 2022, p. 494 - 502
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- 01 Aug 2022
Abstract
Mesenchymal stem cells (MSCs) are remarkable and noteworthy. Identification of markers for MSCs enables the study of their niche in vivo. It has been identified that glioma-associated oncogene 1 positive (Gli1+) cells are mesenchymal stem cells supporting homeostasis and injury repair, especially in the skeletal system and teeth. This review outlines the role of Gli1+ cells as MSC subpopulation in both bones and teeth, suggesting the prospects of Gli1 an + cells in stem cell- based tissue engineering.
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