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This issue of Current Psychiatry Reviews, the first of volume 4, marks our transition from a more conventional “hard copy” format to that of electronic publication. Some of us who came of age in the era prior to the internet have embraced this 21st Century way of doing things with enthusiasm; for others, the prospects of a journal that only exists in the ether so to speak is an unsettling endeavor. There is no doubt, however, that we are ahead of the curve in this regard: electronic publication is more efficient and that it will permit our journal to accomplish our aims of rapid publication of state-of-the-science reviews across a broad range of topics that are of interest to psychiatrists and other mental health professionals. This particular issue of Current Psychiatry Reviews, for example, includes an article examining the elevated risk of Alzheimer's disease among African- Americans by Stephanie Kirbach, two articles on Schizophrenia (Glenn Shean's “Evidence Based Psychosocial Practices and Recovery from Schizophrenia” and “Measures of Functional Status and Quality-of-Life in Schizophrenia” by Mark Price), and articles by Andrew Chanen, Joel Paris, and Mark Zeigenbein reviewing various aspects of Axis II disorders. In addition, Ihsan Salloum - my longtime and excellent collaborator from our days at the University of Pittsburgh Medical Center - has prepared a systematic review on the data on antidepressant treatment of depression in people with substance abuse disorders. I hope that you will enjoy this selection of reviews and that you continue to think of Current Psychiatry Reviews as a potential home for your scholarly reviews.