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- ISSN: 1389-2010
- E-ISSN: 1873-4316
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Mechanisms of Protein Aggregation
- Source: Current Pharmaceutical Biotechnology, Volume 10, Issue 4, Jun 2009, p. 348 - 351
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- 01 Jun 2009
Abstract
Aggregation or reversible self-association of protein therapeutics can arise through a number of different mechanisms. Five common aggregation mechanisms are described and their relations to manufacturing processes to suppress and remove aggregates are discussed.
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