NKT Cells: A Regulator in Both Innate and Acquired Immunity

Ken-ichiro Seino; Masaru Taniguchi

doi:10.2174/1568014053005282

ISSN: 1568-0142
E-ISSN: 1875-6131

NKT Cells: A Regulator in Both Innate and Acquired Immunity
Authors: Ken-ichiro Seino¹ and Masaru Taniguchi²
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¹ Laboratory for Immune Regulation, RIKEN Research Center for Allergy and Immunology, Suehirocho 1-7-22, Tsurumi, Yokohama, Kanagawa 230-0045, Japan. ² Laboratory for Immune Regulation, RIKEN Research Center for Allergy and Immunology, Suehirocho 1-7-22, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
Source: Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents, Volume 4, Issue 1, Feb 2005, p. 59 - 64
DOI: https://doi.org/10.2174/1568014053005282
- Available online: 01 Feb 2005

Abstract

CDd-restricted NKT cells are a unique subset of lymphocytes bridging innate and acquired immunity and mediating both effector and regulatory functions in immune responses. NKT cells are essential for the protection against pathogens or tumors, and also play a regulatory role in transplantation tolerance and autoimmune disease development. This review focuses on the various functions of NKT cells and discusses fundamental mechanisms in NKT cell biology.

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2005-02-01

2025-05-21

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Article Type: Review Article

Keyword(s): cytokines; dendritic cells (dcs); immune system; lymphocytes; natural killer (nk) cells; transcription

NKT Cells: A Regulator in Both Innate and Acquired Immunity

Abstract

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