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2000
Volume 1, Issue 1
  • ISSN: 2666-948X
  • E-ISSN: 2666-9498

Abstract

Background

Silver metal is useful in a variety of fields. Different silver salts exhibit good application in the organic transformation. The use of a green methodology in AgNPs preparation has gained interest of young researchers. Plant systems are employed in the green approach of preparing AgNPs, serving as both a stabilizing and reducing agent. Silver nanoparticles (AgNPs) made from silver salts exhibit a variety of biological activities and may be useful in organic transformation.

Method

AgNPs were synthesized with the use of flower extract from , which acts as a stabilizing and reducing agent.

Result

flower extract is used as a reducing and stabilising agent for preparation of AgNPs. These synthesised AgNPs were characterised by using FTIR, XRD, FE-SEM/EDS, HR-TEM, TGA, and ICP-AES. flower extract was subjected to FTIR and HR-LCMS analysis in order to identify the phytoconstituents that are responsible for the reduction of AgNO. The HR-TEM shows particle size between 8.984340.69669 nm and 19.074641.4384 nm. The size of AgNPs determined by using HR-TEM shows good agreement with XRD particle size. The synthesized AgNPs show excellent antioxidant properties with IC=56.45 μg/mL. The present study confers significant cytotoxic activity against MDA-MB-231 human breast cancer cell line culture (IC= 61.97 µg/ml). The AgNPs show a faster reduction of 4-nitrophenol.

Conclusion

In conclusion, we have prepared AgNPs by using flower extract. The study further concludes that green synthesis of AgNPs has many advantages as compared to chemical methods, such as cost-effectiveness, rapid, and environment-friendly methods. The results indicated that the biosynthesized AgNPs have significant cytotoxic activity against the MDA-MB-231 breast cancer cell line. Further, it indicates that biosynthesized AgNPs can be a potential alternative agent for human breast cancer therapy. The cytotoxic potential can be used for treatments and provides a new method to develop molecules for cancer therapy. The catalytic activity of AgNPs was examined by using the reduction of 4-nitrophenol. It shows that the reduction of 4-nitrophenol in 6 minutes is confirmed by using 1H NMR analysis.

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2024-10-31
2026-02-18

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Environment-friendly Synthesis of AgNPs from Fimbristylis miliacea Flower Extract: Characterization and its Applications as an Antioxidant Activity, Anticancerous Activity and in the Reduction of 4-Nitrophenol
Curr. Engineer. Lett. and Rev. 1, E2666948X325936 (2024); https://doi.org/10.2174/012666948X325936241022054115
/content/journals/celt/10.2174/012666948X325936241022054115
/content/journals/celt/10.2174/012666948X325936241022054115
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  • Article Type:     Research Article
Keyword(s): AgNPs; anticancerous activity; antioxidant activity; Environment-friendly synthesis; Fimbristylis milliciea flower extract; Reduction

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