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image of Study of Brazilian Amazon Honeybees' (Melipona scutellaris and Apis mellifera) Properties in Healing Infected Skin Wounds in Wistar Rats

Abstract

Introduction

In recent decades, studies have begun to analyze the therapeutic properties of honey, specifically in wound healing. The objective of this research was to investigate the tissue repair process of cutaneous wounds infected with in Wistar rats through the application of honey.

Methods

The antibacterial analysis results were satisfactory, showing a reduction in bacteria in the Petri dishes. In the macroscopic analysis, there was a reduction in the wound area in all groups, but the groups treated with honey showed significantly better differences compared to the control group.

Result

In the evaluation of the mean intensity of the inflammatory infiltrate, there was a reduction in the infiltrate in all groups, but no significant difference was observed. In the collagen evaluation, the groups that received treatment with and honey showed a greater deposition of collagen fiber bundles, with a significant difference compared to the control group. After 14 days there was total regeneration of the epidermis in most animals, with a greater amount of collagen fiber formation.

Conclusion

Therefore, the work showed a novelty in terms of the screening of the use of a natural product for wound healing purposes giving prospects for substitution of traditional medicines by honeybee, being a sustainable alternative for human health.

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2024-12-02
2025-03-01

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/content/journals/cbiot/10.2174/0122115501343962241121190220
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Study of Brazilian Amazon Honeybees' (Melipona scutellaris and Apis mellifera) Properties in Healing Infected Skin Wounds in Wistar Rats
Bentham Science Publishers ; https://doi.org/10.2174/0122115501343962241121190220
/content/journals/cbiot/10.2174/0122115501343962241121190220
/content/journals/cbiot/10.2174/0122115501343962241121190220
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  • Article Type:     Research Article
Keywords: Melipona scutellaris ; Staphylococcus aureus ; antibacterial activity ; Honey ; Apis mellifera

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