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2000
Volume 13, Issue 5
  • ISSN: 1574-8936
  • E-ISSN: 2212-392X

Abstract

Background and Objective: Attention deficit hyperactivity disorder (ADHD) is a typical neurodevelopmental disorder occurs in children's early school-age, which often results in serious executive dysfunction. Recent ADHD studies highlight the great potential of non-invasive event-related potential (ERP) technique. It is thus worth combining multiple features to form sensitive and robust biomarkers to distinguish ADHD from normal children. Methods: In this paper, we collected the EEG signals of sixty-eight ADHD children and seventy-three age-match typically developing children during a classic Simon-spatial Stroop task. A channel optimization method was used to select the feature channel. Time-domain features and frequencydomain features were extracted from EEG data. Three classifiers were used to classify ADHD children from typically developing children by using multiple features as well as each single feature. Results: ADHD children showed weaker N2 and P2 signals than typically developing children. Behavior response results showed that, children with ADHD exhibited lower correct response rates, longer average response time and higher data variance. In classification experiment, performance of three classifiers trained on multiple features was much better than that on single feature. Multiple features classification achieved the highest accuracy of 96.6%, while single time-domain and frequencydomain feature only achieved the highest accuracy of 88.10% and 92.85% respectively. All the highest accuracies were achieved on feature channel in inferior parietal cortex. Conclusion: Feature channel generally performed better than empirical channel. The multiple ERP features classification method has a good recognition accuracy, being worth researching in ADHD's auxiliary diagnosis.

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/content/journals/cbio/10.2174/1574893612666171201142836
2018-10-01
2025-05-24
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/content/journals/cbio/10.2174/1574893612666171201142836
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