PredictFold-PSS-3D1D: A Protein Fold Recognition Server for Predicting Folds from the Twilight Zone Sequences.

Kaliappan Ganesan; Subbiah Parthasarathy

doi:10.2174/1574893611308050005

ISSN: 1574-8936
E-ISSN: 2212-392X

PredictFold-PSS-3D1D: A Protein Fold Recognition Server for Predicting Folds from the Twilight Zone Sequences.
By Kaliappan Ganesan and Subbiah Parthasarathy
Source: Current Bioinformatics, Volume 8, Issue 5, Nov 2013, p. 552 - 556
DOI: https://doi.org/10.2174/1574893611308050005
- Available online: 01 Nov 2013

Abstract

The PredictFold-PSS-3D1D is an online protein fold recognition web server used to predict the possible folds from the twilight zone protein sequences. In this server, an improved 3D1D profile method (Ganesan and Parthasarathy, J. Struct. Funct. Genomics, 12, 181-189, 2011) is employed, wherein, the inclusion of predicted secondary structure information improves fold recognition. The PredictFold-PSS-3D1D server accepts amino acid sequences and their predicted secondary structure data as input and aligns them with the 3D1D profiles of known SCOP folds in a database. The alignments are ranked by the z-values and P-values. The top 5 ranks of the SCOP folds from the database are listed along with a link to ‘View SCOP details’. The folds with z-values ≥3.0 and P-values ≤0.05 are indicated as ‘Predicted Fold’ for the given query twilight zone protein sequence. This server is available in our PredictFold web server at http://bioinfo.bdu.ac.in/pss3d1d/.

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2025-05-01

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Article Type: Research Article

Keyword(s): 3D1D profile; protein fold recognition; protein secondary structure server; twilight zone sequences

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PredictFold-PSS-3D1D: A Protein Fold Recognition Server for Predicting Folds from the Twilight Zone Sequences.

Abstract

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