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2000
Volume 15, Issue 1
  • ISSN: 2210-6766
  • E-ISSN: 2210-6774

Abstract

The opioid epidemic continues to make a significant impact on public health across multiple domains. While patients with opioid use disorders (OUD) remain in the face of this epidemic, the effect of the opioid epidemic, including on children and families, remains unheard. The impact of the opioid crisis is felt the most by individuals who do not use opioids themselves, with children being the most vulnerable victims of the opioid epidemic, an aspect of this epidemic that receives far less attention. The socio-ecological model approach is used to increase awareness of the lived experiences of children growing up in households with OUD and to promote the incorporation of treatment considerations based on available research. A literature review was conducted using computer-based searches using PubMed, PsycINFO, Medline, and Google Scholar databases. This entailed searching according to the following keywords (or stems when possible): opioids, opioid overdose, parental opioid use, child maltreatment, resilience, and adverse childhood experiences. Keywords were combined by using the Boolean operators “AND” and “OR”. Additionally, the ancestry approach, where potential studies were identified from the reference sections of existing reviews on the association between opioids and children, was used. Given that prenatal opioid use is extensively studied, and our focus was on lived experiences, studies focused solely on the effects of prenatal opioid use were excluded. Selected studies were varied in scope and methodologies. We reviewed the bibliographies of identified studies for additional studies and used both forward and backward searching. The economic cost of OUD and fatal opioid overdose is staggering and estimated to be about $1.02 trillion. Exposure to parental opioid use in childhood can have a significant impact on children's current and future lives. Conversely, for parents with OUD, children often provide a strong motivation for treatment. Children of adults with OUD are at higher risk of early exposure and initiation of opioid misuse. Opioid exposure in childhood, in turn, is associated with adult opioid misuse and OUD. Screening at healthcare visits is advocated to detect and mitigate the impact of OUD on children. The odds of using school-based mental health services are greater in boys compared to girls. Emerging evidence suggests that boys manifest less resiliency in the face of parental opioid exposure. This indicates a more nuanced understanding of the developmental outcomes of parental opioid exposure.

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References

  1. Adoption and Foster Care Analysis and Reporting SystemPrevalence of parental alcohol or drug abuse as an identified condition of removal in the United States.2020Available from: https://ncsacw.acf.hhs.gov/files/statistics-2020. pdf
  2. AhernN.R. MechlingB. PalumboR. WoodardE. Children of parents with opioid use disorder.J. Psychosoc. Nurs. Ment. Health Serv.2021593283410.3928/02793695‑20201203‑0333301046
    [Google Scholar]
  3. AltekruseS.F. CosgroveC.M. AltekruseW.C. JenkinsR.A. BlancoC. Socioeconomic risk factors for fatal opioid overdoses in the United States: Findings from the mortality disparities in american communities study (MDAC).PLoS One2020151e022796610.1371/journal.pone.022796631951640
    [Google Scholar]
  4. American Academy of Pediatrics. Committee on Substance Abuse (1998). Tobacco, alcohol, and other drugs: The role of the pediatrician in prevention and management of substance abuse.Pediatrics1011 Pt 112512811345974
    [Google Scholar]
  5. AneniK. FernandesC.S.F. HoernerL.A. SzaparyC. Pendergrass BoomerT.M. FiellinL.E. A video game intervention to prevent opioid misuse among older adolescents: Development and preimplementation study.JMIR Serious Games202311e4691210.2196/4691237921851
    [Google Scholar]
  6. ApsleyH.B. BrantK. BrothersS. HarrisonE. SkogsethE. SchwartzR.P. JonesA.A. Pregnancy- and parenting-related barriers to receiving medication for opioid use disorder: A multi-paneled qualitative study of women in treatment, women who terminated treatment, and the professionals who serve them.Women’s Health2024201745505723122418110.1177/1745505723122418138362719
    [Google Scholar]
  7. Bakos-BlockC. NashA.J. CohenA.S. Champagne-LangabeerT. Experiences of parents with opioid use disorder during their attempts to seek treatment: A qualitative analysis.Int. J. Environ. Res. Public Health202219241666010.3390/ijerph19241666036554539
    [Google Scholar]
  8. BerkelC. O’HaraK. EddyJ.M. RhodesC.A. BlakeA. ThomasN. HitaL. HerreraD. WheelerA.C. WolchikS. The prospective effects of caregiver parenting on behavioral health outcomes for children with incarcerated parents: A family resilience perspective.Prev. Sci.20232461198120810.1007/s11121‑023‑01571‑937462777
    [Google Scholar]
  9. BetcherH.K. Vande VoortJ.L. CroarkinP.E. GandhiK.D. ShekunovJ. LarrabeeB.R. LimbeckM.G. RummansT.A. RomanowiczM. Effects of parental opioid use.Prim. Care Companion CNS Disord.201921419m0247410.4088/PCC.19m0247431424700
    [Google Scholar]
  10. BlackwoodC.A. CadetJ.L. Epigenetic and genetic factors associated with opioid use disorder: Are these relevant to african american populations.Front. Pharmacol.20211279836210.3389/fphar.2021.79836235002733
    [Google Scholar]
  11. BrentD.A. HurK. GibbonsR.D. Association between parental medical claims for opioid prescriptions and risk of suicide attempt by their children.JAMA Psychiatry201976994194710.1001/jamapsychiatry.2019.094031116357
    [Google Scholar]
  12. BrodieN. KeimJ.L. SilberholzE.A. SpectorN.D. PattishallA.E. Promoting resilience in vulnerable populations: Focus on opioid-exposed children, siblings of children with special healthcare needs and support for children through school-based interventions.Curr. Opin. Pediatr.201931115716510.1097/MOP.000000000000072230531404
    [Google Scholar]
  13. BrowneC.J. GodinoA. SaleryM. NestlerE.J. Epigenetic mechanisms of opioid addiction.Biol. Psychiatry2020871223310.1016/j.biopsych.2019.06.02731477236
    [Google Scholar]
  14. BrundageS. LevineC. The ripple effect: The impact of the opioid epidemic on children and families.2019Available from: https://media.uhfnyc.org/filer_public/17/2c/172ca968-43aa-45f9-a290-50018e85a9d8/uhf-opioids-20190315.pdf
  15. CarpenterC.S. McClellanC.B. ReesD.I. Economic conditions, illicit drug use, and substance use disorders in the United States.J. Health Econ.201752637310.1016/j.jhealeco.2016.12.00928235697
    [Google Scholar]
  16. CashR.E. KinsmanJ. CroweR.P. RivardM.K. FaulM. PanchalA.R. Naloxone administration frequency during emergency medical service events — United States, 2012–2016.MMWR Morb. Mortal. Wkly. Rep.2018673185085310.15585/mmwr.mm6731a230091966
    [Google Scholar]
  17. ChoiS. RyanJ.P. Completing substance abuse treatment in child welfare: The role of co-occurring problems and primary drug of choice.Child Maltreat.200611431332510.1177/107755950629260717043316
    [Google Scholar]
  18. Clemans-CopeL. LynchV. EpsteinM. KenneyG.M. Opioid and substance use disorder and receipt of treatment among parents living with children in the United States, 2015-2017.Ann. Fam. Med.201917320721110.1370/afm.238931085524
    [Google Scholar]
  19. CrowleyD.M. ConnellC.M. JonesD. DonovanM.W. Considering the child welfare system burden from opioid misuse: Research priorities for estimating public costs.Am. J. Manag. Care20192513Suppl.S256S26331361428
    [Google Scholar]
  20. DalvieS. MaihoferA.X. ColemanJ.R.I. BradleyB. BreenG. BrickL.A. ChenC.Y. ChoiK.W. DuncanL.E. GuffantiG. HaasM. HarnalS. LiberzonI. NugentN.R. ProvostA.C. ResslerK.J. TorresK. AmstadterA.B. Bryn AustinS. BakerD.G. BolgerE.A. BryantR.A. CalabreseJ.R. DelahantyD.L. FarrerL.A. FeenyN.C. FloryJ.D. ForbesD. GaleaS. GautamA. GelernterJ. HammamiehR. JettM. JunglenA.G. KaufmanM.L. KesslerR.C. KhanA. KranzlerH.R. LeboisL.A.M. MarmarC. MavissakalianM.R. McFarlaneA. DonnellM.O. OrcuttH.K. PietrzakR.H. RisbroughV.B. RobertsA.L. RothbaumA.O. Roy-ByrneP. RuggieroK. SeligowskiA.V. SheerinC.M. SiloveD. SmollerJ.W. SteinM.B. TeicherM.H. UrsanoR.J. Van HooffM. WinternitzS. WolffJ.D. YehudaR. ZhaoH. ZoellnerL.A. SteinD.J. KoenenK.C. NievergeltC.M. Genomic influences on self-reported childhood maltreatment.Transl. Psychiatry20201013810.1038/s41398‑020‑0706‑032066696
    [Google Scholar]
  21. DasguptaN. BeletskyL. CiccaroneD. Opioid crisis: No easy fix to its social and economic determinants.Am. J. Public Health2018108218218610.2105/AJPH.2017.30418729267060
    [Google Scholar]
  22. DavisL. ShlaferR.J. Mental health of adolescents with currently and formerly incarcerated parents.J. Adolesc.201754112013410.1016/j.adolescence.2016.10.00628011442
    [Google Scholar]
  23. DaweS. HarnettP. Reducing potential for child abuse among methadone-maintained parents: Results from a randomized controlled trial.J. Subst. Abuse Treat.200732438139010.1016/j.jsat.2006.10.00317481461
    [Google Scholar]
  24. DaytonT. The setup: Living with addiction. Adapted from the process study guide for the national association for children of alcoholics congregational leadership training.2012Available from: http://www.nacoa.net/pdfs/The%20Setup.pdf
  25. DeolE. SiddiquiZ. ParachaA. MujovicH. AbroZ. ChangS.R. AbidA. TylerJ.H. RehmanH. BeraS. KhanZ. VasireddyS. ChalichamaJ. FidahussainA. ParachaM. AhmedZ. AlyasiryN. EngelhardtM. KadariyaB. OdehA. PitchiahM. RaoN. RueveJ. CepeleI. MeyerD. Exploring the link between ACEs and opioid use: A systematic review.J. Opioid. Manag.202319434336410.5055/jom.2023.079137644792
    [Google Scholar]
  26. DeVoreE.R. GinsburgK.R. The protective effects of good parenting on adolescents.Curr. Opin. Pediatr.200517446046510.1097/01.mop.0000170514.27649.c916012256
    [Google Scholar]
  27. Dolbin-MacNabM.L. O’ConnellL.M. Grandfamilies and the opioid epidemic: A systemic perspective and future priorities.Clin. Child Fam. Psychol. Rev.202124220722310.1007/s10567‑021‑00343‑733491118
    [Google Scholar]
  28. SpencerM. MiniñoA. WarnerM. Drug overdose deaths in the United States, 2001-2021.NCHS Data Brief20224571810.15620/cdc:12255636598401
    [Google Scholar]
  29. DubeS.R. FelittiV.J. DongM. ChapmanD.P. GilesW.H. AndaR.F. Childhood abuse, neglect, and household dysfunction and the risk of illicit drug use: The adverse childhood experiences study.Pediatrics2003111356457210.1542/peds.111.3.56412612237
    [Google Scholar]
  30. DubeS. R. MillerJ. W. BrownD. W. GilesW. H. FelittiV. J. DongM. AndaR. F. Adverse childhood experiences and the association with ever using alcohol and initiating alcohol use during adolescence.J Adolesc Health2006384e44110.1016/j.jadohealth.2005.06.006
    [Google Scholar]
  31. Fals-StewartW. O’FarrellT.J. BirchlerG.R. Behavioral couples therapy for substance abuse: Rationale, methods, and findings.Sci. Pract. Perspect.200422304110.1151/spp04223018552731
    [Google Scholar]
  32. FederK.A. LetourneauE.J. BrookJ. Children in the opioid epidemic: Addressing the next generation’s public health crisis.Pediatrics20191431e2018165610.1542/peds.2018‑165630514782
    [Google Scholar]
  33. FelittiV.J. Origins of addictive behavior: Evidence from a study of stressful chilhood experiences.Prax. Kinderpsychol. Kinderpsychiatr.200352854755914619682
    [Google Scholar]
  34. FelittiV.J. AndaR.F. NordenbergD. WilliamsonD.F. SpitzA.M. EdwardsV. KossM.P. MarksJ.S. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The adverse childhood experiences (ACE) study.Am. J. Prev. Med.199814424525810.1016/S0749‑3797(98)00017‑89635069
    [Google Scholar]
  35. FlorenceC. LuoF. RiceK. The economic burden of opioid use disorder and fatal opioid overdose in the United States, 2017.Drug Alcohol Depend.202121810835010.1016/j.drugalcdep.2020.10835033121867
    [Google Scholar]
  36. FordJ.A. PomykaczC.R. OrtizK. McCabeS.E. SchepisT.S. Educational attainment and prescription drug misuse: The importance of push and pull factors for dropping out.J. Crim. Justice20206610163610.1016/j.jcrimjus.2019.10163632863457
    [Google Scholar]
  37. FreisthlerB. MichaelsN. WolfJ.P. Families in crisis: The relationship between opioid overdoses and child maltreatment in neighborhood areas.J. Stud. Alcohol Drugs202283114515410.15288/jsad.2022.83.14535040770
    [Google Scholar]
  38. GaitherJ.R. ShabanovaV. LeventhalJ.M. US national trends in pediatric deaths from prescription and illicit opioids, 1999-2016.JAMA Netw. Open201818e18655810.1001/jamanetworkopen.2018.655830646334
    [Google Scholar]
  39. Gance-ClevelandB. MaysM.Z. School-based support groups for adolescents with a substance-abusing parent.J. Am. Psychiatr. Nurses Assoc.200814429730910.1177/107839030832122321665773
    [Google Scholar]
  40. Gance-ClevelandB. MaysM.Z. SteffenA. Association of adolescent physical and emotional health with perceived severity of parental substance abuse.J. Spec. Pediatr. Nurs.2008131152510.1111/j.1744‑6155.2008.00130.x18096009
    [Google Scholar]
  41. GhertnerR. National and state estimates of children with parents using substances, 2015-2019.2022Available from: https://www.aspe.hhs.gov/sites/default/files/documents/faa1b19e66053008e89782914f0aa693/children-at-risk-of-sud.pdf
  42. GhertnerR. AliM. M. Treatment for opioid use disorder may reduce substantiated cases of child abuse and neglect.2021Available from: https://opioid-resource-connector.org/index.php/resources/treatment-for-opioid-use-disorder-may-reduce-substantiated-cases-of-child-abuse-and neglect.
  43. GhertnerR. GrovesL. The opioid crisis and economic opportunity: Geographic and economic trends. U.S. Department of health and human services.2018Available from: https://aspe.hhs.gov/sites/default/files/private/pdf/259261/ASPEEconomicOpportunityOpioidCrisis.pdf
  44. GhertnerR. WatersA. RadelL. CrouseG. The role of substance use in child welfare caseloads.Child. Youth Serv. Rev.201890839310.1016/j.childyouth.2018.05.015
    [Google Scholar]
  45. GiffordE.J. Eldred KozeckeL. GolonkaM. HillS.N. CostelloE.J. ShanahanL. CopelandW.E. Association of parental incarceration with psychiatric and functional outcomes of young adults.JAMA Netw. Open201928e191000510.1001/jamanetworkopen.2019.1000531441942
    [Google Scholar]
  46. GigliK. ValliveduS. Social determinants of health needs among children and adolescents with opioid-related hospitalizations.J. Pediatr. Health Care202236439639710.1016/j.pedhc.2022.05.013
    [Google Scholar]
  47. GomesT. TadrousM. MamdaniM.M. PatersonJ.M. JuurlinkD.N. The burden of opioid-related mortality in the United States.JAMA Netw. Open201812e18021710.1001/jamanetworkopen.2018.021730646062
    [Google Scholar]
  48. GrayP. FraserP. Housing and heroin use: The role of floating support.Drugs Educ. Prev. Policy200512426927810.1080/09687630500049684
    [Google Scholar]
  49. GuarinoH. Mateu-GelabertP. QuinnK. SirikantrapornS. RugglesK.V. SyckesC. GoodbodyE. JessellL. FriedmanS.R. Adverse childhood experiences predict early initiation of opioid use behaviors.Frontiers in Sociology2021662039510.3389/fsoc.2021.62039534055961
    [Google Scholar]
  50. HaggertyK.P. SkinnerM. FlemingC.B. GaineyR.R. CatalanoR.F. Long‐term effects of the focus on families project on substance use disorders among children of parents in methadone treatment.Addiction2008103122008201610.1111/j.1360‑0443.2008.02360.x18855808
    [Google Scholar]
  51. HallM.T. WilfongJ. HuebnerR.A. PoszeL. WillauerT. Medication-assisted treatment improves child permanency outcomes for opioid-using families in the child welfare system.J. Subst. Abuse Treat.201671636710.1016/j.jsat.2016.09.00627776680
    [Google Scholar]
  52. HansenH. JordanA. PloughA. AlegriaM. CunninghamC. OstrovskyA. Lessons for the opioid crisis—Integrating social determinants of health into clinical care.Am. J. Public Health2022112S2S109S11110.2105/AJPH.2021.30665135349328
    [Google Scholar]
  53. HansonK.E. SaulD.H. VanderploegJ.J. PainterM. AdnopozJ. Family-based recovery: An innovative in-home substance abuse treatment model for families with young children.Child Welfare201594416118326827481
    [Google Scholar]
  54. HansonR.F. LangJ. A critical look at trauma-informed care among agencies and systems serving maltreated youth and their families.Child Maltreat.20162129510010.1177/107755951663527426951344
    [Google Scholar]
  55. HeJ. YanX. WangR. ZhaoJ. LiuJ. ZhouC. ZengY. Does childhood adversity lead to drug addiction in adulthood? A study of serial mediators based on resilience and depression.Front. Psychiatry20221387145910.3389/fpsyt.2022.87145935509889
    [Google Scholar]
  56. HedegaardH Drug overdose deaths in the United States, 1999–2016.2017Available from: https://www.cdc.gov/nchs/products/databriefs/db294.htm
  57. HollingsworthA. RuhmC.J. SimonK. Macroeconomic conditions and opioid abuse.J. Health Econ.20175622223310.1016/j.jhealeco.2017.07.00929128677
    [Google Scholar]
  58. HserY.I. HoffmanV. GrellaC.E. AnglinM.D. A 33-year follow-up of narcotics addicts.Arch. Gen. Psychiatry200158550350810.1001/archpsyc.58.5.50311343531
    [Google Scholar]
  59. HuebnerR.A. HallM.T. WaltonM.T. SmeadE. WillauerT. PoszeL. The sobriety treatment and recovery teams program for families with parental substance use: Comparison of child welfare outcomes through 12 months post-intervention.Child Abuse Negl.202112010526010.1016/j.chiabu.2021.10526034391128
    [Google Scholar]
  60. HulseyE.G. LiY. HackerK. WilliamsK. CollinsK. DaltonE. Potential emerging risks among children following parental opioid-related overdose death.JAMA Pediatr.2020174550350410.1001/jamapediatrics.2020.061332282028
    [Google Scholar]
  61. HulseyJ. ZawislakK. Sawyer-MorrisG. EarnshawV. Stigmatizing imagery for substance use disorders: A qualitative exploration.Health Justice20231112810.1186/s40352‑023‑00229‑637402079
    [Google Scholar]
  62. JohnsonM.E. AlejandroA.D. VroomE.B. Homegrown: Parent and sibling substance abuse linked to opioid misuse among justice-involved children.J. Child Fam. Stud.20233251495150310.1007/s10826‑022‑02417‑837605752
    [Google Scholar]
  63. KellerT.E. CatalanoR.F. HaggertyK.P. FlemingC.B. Parent figure transitions and delinquency and drug use among early adolescent children of substance abusers.Am. J. Drug Alcohol Abuse200228339942710.1081/ADA‑12000673412211358
    [Google Scholar]
  64. KimS. KwokS. MayesL.C. PotenzaM.N. RutherfordH.J.V. StrathearnL. Early adverse experience and substance addiction: Dopamine, oxytocin, and glucocorticoid pathways.Ann. N. Y. Acad. Sci.201713941749110.1111/nyas.1314027508337
    [Google Scholar]
  65. KugenerT. WiethoffI. van MastrigtG. van den BergB. EversS.M.A.A. Economic evaluations of interventions focusing on child abuse and neglect in high-income countries: A systematic review.Front. Psychiatry202314103103710.3389/fpsyt.2023.103103737415695
    [Google Scholar]
  66. LaneW.G. DubowitzH. FrickK.D. SemiatinJ. MagderL. Cost effectiveness of SEEK: A primary care-based child maltreatment prevention model.Child Abuse Negl.202111110480910.1016/j.chiabu.2020.10480933203542
    [Google Scholar]
  67. LipariR. N. Van HornS. L. Children living with parents who have a substance use disorder.The CBHSQ Report.Rockville (MD)Substance Abuse and Mental Health Services Administration (US)2017 https://pubmed.ncbi.nlm.nih.gov/29144715/ 29144715
    [Google Scholar]
  68. MarshS. DobsonR. MaddisonR. The relationship between household chaos and child, parent, and family outcomes: A systematic scoping review.BMC Public Health202020151310.1186/s12889‑020‑08587‑832316937
    [Google Scholar]
  69. MechlingB.M. AhernN.R. PalumboR. Applying ambiguous loss theory to children of parents with an opioid use disorder.J. Child Adolesc. Psychiatr. Nurs.2018312-3536010.1111/jcap.1220930298538
    [Google Scholar]
  70. MechlingB.M. AhernN.R. PalumboR. Promoting resilience for children of parents with opioid use disorder: A pilot study of a directed intervention.J. Child Adolesc. Psychiatr. Nurs.202134319119810.1111/jcap.1231933870601
    [Google Scholar]
  71. MeinhoferA. Angleró-DíazY. Trends in foster care entry among children removed from their homes because of parental drug use, 2000 to 2017.JAMA Pediatr.2019173988188310.1001/jamapediatrics.2019.173831305925
    [Google Scholar]
  72. MeulewaeterF. De SchauwerE. De PauwS.S.W. VanderplasschenW. “I grew up amidst alcohol and drugs:” A qualitative study on the lived experiences of parental substance use among adults who developed substance use disorders themselves.Front. Psychiatry20221376880210.3389/fpsyt.2022.76880235185647
    [Google Scholar]
  73. MillerT. HendrieD. Substance Abuse Prevention Dollars and Cents: A Cost-Benefit Analysis.Substance Abuse and Mental Health Services Administration2008
    [Google Scholar]
  74. MiniñoA.M. GarnettM.F. SpencerM.R. Drug overdose deaths in the United States, 2002–2022.2024Available from: https://www.cdc.gov/nchs/products/databriefs/db491.htm
  75. MirickR.G. SteenrodS.A. Opioid use disorder, attachment, and parenting: Key concerns for practitioners.Child Adolesc. Social Work J.201633654755710.1007/s10560‑016‑0449‑1
    [Google Scholar]
  76. MorelandA. CrumK. RostadW.L. StefanescuA. WhitakerD. Examining an in-home behavioral parent training protocol among parents who use substances involved child welfare: Effectiveness of safecare.Child Maltreat.202227467168210.1177/1077559521104694034730030
    [Google Scholar]
  77. NegerE.N. PrinzR.J. Interventions to address parenting and parental substance abuse: Conceptual and methodological considerations.Clin. Psychol. Rev.201539718210.1016/j.cpr.2015.04.00425939033
    [Google Scholar]
  78. NosratiE. Kang-BrownJ. AshM. McKeeM. MarmotM. KingL.P. Economic decline, incarceration, and mortality from drug use disorders in the USA between 1983 and 2014: An observational analysis.Lancet Public Health201947e326e33310.1016/S2468‑2667(19)30104‑531279417
    [Google Scholar]
  79. NovakP. FederK.A. AliM.M. ChenJ. Behavioral health treatment utilization among individuals with co-occurring opioid use disorder and mental illness: Evidence from a national survey.J. Subst. Abuse Treat.201998475210.1016/j.jsat.2018.12.00630665603
    [Google Scholar]
  80. NystrandC. GebreslassieM. SsegonjaR. FeldmanI. SampaioF. A systematic review of economic evaluations of public health interventions targeting alcohol, tobacco, illicit drug use and problematic gambling: Using a case study to assess transferability.Health Policy20211251547410.1016/j.healthpol.2020.09.00233069504
    [Google Scholar]
  81. Onigu-OtiteE. IdiculaS. Introducing ACEs (adverse childhood experiences) and resilience to first-year medical students.MedEdPORTAL2020161096410.15766/mep_2374‑8265.1096432964120
    [Google Scholar]
  82. Onigu-OtiteE.M.D. JamoraM.M.D. Abuse and Neglect: Johns Hopkins Psychiatry Guide.Baltimore, MDJohns Hopkins Psychiatry Guide2017
    [Google Scholar]
  83. OswaldL.M. DunnK.E. SeminowiczD.A. StorrC.L. Early life stress and risks for opioid misuse: Review of data supporting neurobiological underpinnings.J. Pers. Med.202111431510.3390/jpm1104031533921642
    [Google Scholar]
  84. PalumboR. MechlingB.M. AhernN.R. Parental opioid use disorder: Examining their children’s experiences, needs, and road to resilience.J. Child Adolesc. Psychiatr. Nurs.2022351243710.1111/jcap.1234434342918
    [Google Scholar]
  85. ParkS.E. MosleyJ.E. GroganC.M. PollackH.A. HumphreysK. D’AunnoT. FriedmannP.D. Patient-centered care’s relationship with substance use disorder treatment utilization.J. Subst. Abuse Treat.202011810812510.1016/j.jsat.2020.10812532972650
    [Google Scholar]
  86. ParkS.H. VidelockE.J. ShihW. PressonA.P. MayerE.A. ChangL. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity.Neurogastroenterol. Motil.20162881252126010.1111/nmo.1282627061107
    [Google Scholar]
  87. RadelL. BaldwinM. CrouseG. GhertnerR. WatersA. Substance use, the opioid epidemic, and the child welfare system: Key findings from a mixed methods study.2018Available from: https://aspe.hhs.gov/
  88. RanapurwalaS.I. ShanahanM.E. AlexandridisA.A. ProescholdbellS.K. NaumannR.B. EdwardsD.Jr MarshallS.W. Opioid overdose mortality among former north carolina inmates: 2000–2015.Am. J. Public Health201810891207121310.2105/AJPH.2018.30451430024795
    [Google Scholar]
  89. RiggK.K. JohnsonM.E. Preventing adolescent opioid misuse: Racial/ethnic differences in the protective effects of extracurricular activities.J. Stud. Alcohol Drugs202283340241110.15288/jsad.2022.83.40235590181
    [Google Scholar]
  90. Roley-RobertsM.E. EdreesH. ThomasJ. WeberS. RamseyR. WaltonJ. WitwerA. Impact of an asynchronous training for the early intervention and childcare workforce addressing the developmental impact of the opioid crisis on young children.Matern. Child Health J.20232781361136910.1007/s10995‑023‑03679‑437264219
    [Google Scholar]
  91. RomanowiczM. Vande VoortJ.L. ShekunovJ. OesterleT.S. ThusiusN.J. RummansT.A. CroarkinP.E. KarpyakV.M. LynchB.A. SchakK.M. The effects of parental opioid use on the parent–child relationship and children’s developmental and behavioral outcomes: A systematic review of published reports.Child Adolesc. Psychiatry Ment. Health2019131510.1186/s13034‑019‑0266‑330651753
    [Google Scholar]
  92. SahkerE. AliS.R. ArndtS. Employment recovery capital in the treatment of substance use disorders: Six-month follow-up observations.Drug Alcohol Depend.201920510762410.1016/j.drugalcdep.2019.10762431645013
    [Google Scholar]
  93. SarfiM. EikemoM. Welle-StrandG.K. MullerA.E. LehmannS. Mental health and use of health care services in opioid-exposed school-aged children compared to foster children.Eur. Child Adolesc. Psychiatry202231349550910.1007/s00787‑021‑01728‑333590310
    [Google Scholar]
  94. Drug Overdose Death Rates 1999 - 2021.Available from: https://nida.nih.gov/research-topics/trends-statistics/overdose-death-rates#:~:text=More%20than%2070%25%20of%20deaths,remained%20steady%20
  95. Social Determinants of Health - Healthy People 2030.Available from: https://health.gov/healthypeople/priority-areas/social-determinants-health
  96. SiegelJ.P. Emotional regulation in adolescent substance use disorders: Rethinking risk.J. Child Adolesc. Subst. Abuse2015242677910.1080/1067828X.2012.761169
    [Google Scholar]
  97. SkinnerM.L. HaggertyK.P. FlemingC.B. CatalanoR.F. Predicting functional resilience among young-adult children of opiate-dependent parents.J. Adolesc. Health200944328329010.1016/j.jadohealth.2008.07.02019237115
    [Google Scholar]
  98. SteinM.D. ContiM.T. KenneyS. AndersonB.J. FloriJ.N. RisiM.M. BaileyG.L. Adverse childhood experience effects on opioid use initiation, injection drug use, and overdose among persons with opioid use disorder.Drug Alcohol Depend.201717932532910.1016/j.drugalcdep.2017.07.00728841495
    [Google Scholar]
  99. SteinS. SwerlickA. ChokshiB. Employing an adaptive leadership framework to childhood adversity screening.Pediatrics20201451e2018382010.1542/peds.2018‑382031892520
    [Google Scholar]
  100. Trauma-Informed Care in Behavioral Health Services.Rockville (MD)Substance Abuse and Mental Health Services Administration (US)2014
    [Google Scholar]
  101. Key Substance Use and Mental Health Indicators in the United States: Results from the 2017 National Survey on Drug Use and Health.2018Available from: https://www.samhsa.gov/data/sites/default/files/cbhsq-reports/NSDUHFFR2017/NSDUHFFR2017.pdf
  102. SwainJ.E. HoS.S. FoxH. GarryD. BrummelteS. Effects of opioids on the parental brain in health and disease.Front. Neuroendocrinol.20195410076610.1016/j.yfrne.2019.10076631128130
    [Google Scholar]
  103. TemcheffC.E. LetarteM.J. BoutinS. MarcilK. Common components of evidence-based parenting programs for preventing maltreatment of school-age children.Child Abuse Negl.20188022623710.1016/j.chiabu.2018.02.00429631254
    [Google Scholar]
  104. Title IV-E Prevention Services Clearinghouse, (2021). Safe Environment for Every Kid (SEEK) U (2021).Available from: https://preventionservices.acf.hhs.gov/programs/601/show
  105. TrustW. B. Pain in the nation: The drug, alcohol and suicide crises and need for a national resilience strategy.2023Available from: https://www.tfah.org/report-details/pain-in-the-nation/
  106. U.S. Census Bureau. Annual Social and Economic SupplementChildren in kinship care: Kids count data center.2023Available from: https://datacenter.aecf.org/data/tables/10455-children-in-kinship-care?loc=1&loct=2#detailed/1/any/false/2554,1757/any/20160,20161
  107. UngarM. GhazinourM. RichterJ. Annual research review: What is resilience within the social ecology of human development?J. Child Psychol. Psychiatry201354434836610.1111/jcpp.1202523215898
    [Google Scholar]
  108. VenkataramaniA.S. BairE.F. O’BrienR.L. TsaiA.C. Association between automotive assembly plant closures and opioid overdose mortality in the United States.JAMA Intern. Med.2020180225426210.1001/jamainternmed.2019.568631886844
    [Google Scholar]
  109. VolkowN.D. BlancoC. The changing opioid crisis: Development, challenges and opportunities.Mol. Psychiatry202126121823310.1038/s41380‑020‑0661‑432020048
    [Google Scholar]
  110. WallinC.M. BowenS.E. BrummelteS. Opioid use during pregnancy can impair maternal behavior and the Maternal Brain Network: A literature review.Neurotoxicol. Teratol.20218610697610.1016/j.ntt.2021.10697633812002
    [Google Scholar]
  111. WernerM.J. JoffeA. GrahamA.V. Screening, early identification, and office-based intervention with children and youth living in substance-abusing families.Pediatrics19991035 Pt 2Suppl. 21099111210.1542/peds.103.S2.109910224197
    [Google Scholar]
  112. WilsonJ.D. AbebeK.Z. KraemerK. LiebschutzJ. MerlinJ. MillerE. KelleyD. DonohueJ. Trajectories of opioid use following first opioid prescription in opioid-naive youths and young adults.JAMA Netw. Open202144e21455210.1001/jamanetworkopen.2021.455233885777
    [Google Scholar]
  113. WinstanleyE.L. StoverA.N. The impact of the opioid epidemic on children and adolescents.Clin. Ther.20194191655166210.1016/j.clinthera.2019.06.00331303278
    [Google Scholar]
  114. World Health Organization (2023)Social Determinants of Health (2023).Available from: https://www.who.int/health-topics/social-determinants-of-health#tab= tab_1
  115. ZhongB.L. ChanS.S.M. LiuT.B. ChiuH.F.K. Nonfatal suicidal behaviors of chinese rural‐to‐urban migrant workers: Attitude toward suicide matters.Suicide Life Threat. Behav.20194951199120810.1111/sltb.1251930315652
    [Google Scholar]
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