Methods and Procedures for the Synthesis of 2- Deoxy-D-Glucose
- Authors: Raman Singh1, Vidushi Gupta2, Kuldeep Singh3
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View Affiliations Hide AffiliationsAffiliations: 1 Department of Applied Chemistry, Amity University, Madhya Pradesh, Gwalior 474005, India 2 Department of Chemistry, Indian Institute of Science Education and Research, Mohali, Punjab, India 3 Department of Applied Chemistry, Amity University, Madhya Pradesh, Gwalior-474005, India
- Source: 2-Deoxy-D-Glucose: Chemistry and Biology , pp 12-28
- Publication Date: November 2024
- Language: English
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Many synthetic procedures for preparing 2-deoxy-D-glucose (2DG) are available in the literature. The synthesis of 2DG involves the modification of glucose at 2-position. Several methods to synthesize 2DG include glucose nitrosation and reductive amination of 2-deoxy-D-arabinose. These methods are highly efficient and produce high yields of 2DG. This chapter discusses various methods for synthesizing 2DG and their advantages and disadvantages. This chapter describes the different approaches for synthesizing 2DG and how the choice of method affects its purity, yield, and properties.
Hardbound ISBN:
9789815305166
Ebook ISBN:
9789815305159
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