The Implication of Chromene Derivatives in Bioactive Admixtures
- Authors: Dheeraj Bisht1, Deepak Sati2, Rajeshwar Kamal Kant Arya3, Amit Kumar Nigam4, Monu Kumar Shukla5, Deepak Kumar6
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View Affiliations Hide AffiliationsAffiliations: 1 Department of Pharmaceutical Sciences, Sir J. C. Bose Technical Campus Bhimtal, Kumaun University, Nainital 263136, Uttarakhand, India 2 Department of Pharmaceutical Sciences, Sir J. C. Bose Technical Campus Bhimtal, Kumaun University, Nainital-263136, Uttarakhand, India 3 Department of Pharmaceutical Sciences, Sir J. C. Bose Technical Campus Bhimtal, Kumaun University, Nainital-263136, Uttarakhand, India 4 Goel Institute of Pharmacy and Sciences, Lucknow -226005, India 5 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, India 6 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, India
- Source: The Role of Chromenes in Drug Discovery and Development , pp 225-234
- Publication Date: August 2023
- Language: English
Chromene is a heterocyclic scaffold and can be obtained from the natural origin (from different fractions of the plant extracts), synthetic origin as well as mineral origin. The nucleus of the scaffold possesses the ability to interact with different biological targets and thus is medicinally active. Chromene derivatives obtained from different origins are reported to possess pharmacological activities such as antitumor, antibacterial, anti-inflammatory, antithrombotic, and antipsychotic activities. Many chromene-based admixtures are reported to possess different bioactivities. Many derivatives of chromene, such as isomiroestrol, deoxymiroestrol, and miroestrol have been investigated as phytoestrogens. Along with therapeutic potencies, chromene glycosides have safety, efficacy, and stability in the form of herbal drugs and cosmetics. So, the chapter focuses on chromene derivatives, their biological sources, respective bioactivities, and recent advancements. nbsp;
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