Lipoidal Carrier as Drug Delivery System
- Authors: Bina Gidwani1, Priya Namdeo2, Sakshi Tiwari3, Atul Tripathi4, Ravindra Kumar Pandey5, Shiv Shankar Shukla6, Veenu Joshi7, Vishal Jain8, Suresh Thareja9, Amber Vyas10
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View Affiliations Hide AffiliationsAffiliations: 1 Columbia Institute of Pharmacy, Raipur (C.G), India 2 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G), India 3 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G), India 4 Peoples Institute of Pharmacy & Research Centre, Bhopal, (M.P.), India 5 Columbia Institute of Pharmacy, Raipur (C.G), India 6 Columbia Institute of Pharmacy, Raipur (C.G), India 7 Center of Basic Science, Pt. Ravishankar Shukla University, Raipur (C.G), India 8 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G), India 9 Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab Bathinda, Punjab 151001, India 10 University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G), India
- Source: Nanoparticles and Nanocarriers Based Pharmaceutical Preparations , pp 273-302
- Publication Date: December 2022
- Language: English
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The delivery system plays a vital role in managing the pharmacokinetics and pharmacodynamics of a drug. The size of the carrier system contributes to its pharmacological action. Lipid-based carriers refer to the formulations containing a dissolved or suspended drug in lipidic excipients. Lipoidal systems as carriers are achieving heights due to their significant lipid nature and the size of particles in the delivery system. The micro/nano-sized lipid-based carriers possess versatility in improving the physic-chemical properties of drugs. Also, they are biocompatible and can be administered through all possible routes. Lipid-based drug delivery carrier systems of new and existing formulations can be commercialized to achieve the desired range of product specifications. Solubility of the drug in various lipids is a key factor in the development of the delivery system. Lipids as functional excipients are compatible with solid, liquid, and semi-solid dosage forms. Besides improving/enhancing the solubility and bioavailability, lipids provide multiple broad-based applications in the pharmaceutical delivery system.
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