Biologically Active Quassinoids and Their Chemistry: Potential Leads for Drug Design
- Authors: Zhengming Guo, Suryanarayana Vangapandu, Robert W. Sindelar, Larry A. Walker4, Robert D. Sindelar5
-
View Affiliations Hide AffiliationsAffiliations: 4 Department of Medicinal Chemistry and Laboratory for Applied Drug Design and Synthesis, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, B. C., V6T1Z3, Canada 5 Department of Medicinal Chemistry and Laboratory for Applied Drug Design and Synthesis, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, B. C., V6T1Z3, Canada
- Source: Frontiers in Medicinal Chemistry: Volume 4 , pp 285-308
- Publication Date: January 2009
- Language: English
Preview this chapter:
Biologically Active Quassinoids and Their Chemistry: Potential Leads for Drug Design, Page 1 of 1
< Previous page | Next page > /docserver/preview/fulltext/9781608052073/chapter-9-1.gif
Quassinoids are highly oxygenated triterpenes, which were isolated as bitter principles from the plants of Simaroubaceae family. Their synthesis has attracted much attention because of the wide spectrum of their biological properties. The most prevalent quassinoids have C-20 picrasane skeleton, some known as bruceolides as they were isolated from the genus Brucea, which showed marked antileukemic and antimalarial activities.
Hardbound ISBN:
9781608053469
Ebook ISBN:
9781608052073
-
From This Site
/content/books/9781608052073.chapter-9dcterms_subject,pub_keyword-contentType:Journal105
/content/books/9781608052073.chapter-9
dcterms_subject,pub_keyword
-contentType:Journal
10
5
Chapter
content/books/9781608052073
Book
false
en
