Bentham Science Publishers

Despite an increase in life expectancy over the past 20 years, the number of novel, multi-drug resistant microorganisms has also risen dramatically. To reduce the risk of reemerging infections, and limit the spread of multidrug resistant microorganisms, it is urgently necessary to develop safe and effective therapeutic countermeasures. New antimicrobial chemicals are mostly produced with the help of microorganisms, and the bulk of medications now on the market are of this type. The use of high therapeutic screening and recent developments in analytical instrumentation has allowed the researchers to identify novel antimicrobial compounds from bacteria, fungi, plants, mushrooms, algae, and other sources more quickly. The second volume of Frontiers in Antimicrobial Agents highlights the ongoing requirement for researching and creating novel antimicrobial medications. Current Trends in the Identification and Development of Antimicrobial Agents aims to bring together the expertise of notable academics to examine all facets of antimicrobial research while keeping recent advancements in perspective. Antibiotic discovery, sources of novel antimicrobial chemicals, developing and reemerging microbial infections, various elements of drug resistance, and the need for antimicrobial medications in the future are all covered in this book. It is a timely reference for anyone involved in the discovery and development of new drugs, including microbiologists, biotechnologists, pharmacologists, doctors, and researchers.

The book gives a comprehensive overview of the evolving landscape of cyber-physical systems (CPS) with a primary focus on security challenges and innovative solutions. CPS, encompassing a wide array of applications from e-Health to smart grid and industry automation, is explored in depth through eight edited reviews.

The book starts with an exploration of various threat detection and prevention techniques in IoT environments, followed by discussions on security in smart grid cyber-physical systems, and the integration of cyber-physical systems with game theory. It also covers important topics such as cyber-physical systems in healthcare, augmented reality challenges, network and computer forensic frameworks, and a review of industrial critical infrastructure perspectives.

The journey from traditional data warehouses to data lakes is thoroughly examined, shedding light on the evolution of data storage methods. The final chapter explains intrusion detection in industrial critical infrastructure, reviewing feature selection and classification models. By navigating through these topics, the book equips readers with a comprehensive understanding of cybersecurity challenges and solutions in an era of automation and IoT technologies.

This book is intended for a diverse readership, including professionals, researchers, and technology enthusiasts keen on exploring the intricacies of CPS, IoT security, data storage evolution, and industrial infrastructure protection.

Key Features:

-Analytical insights into cyber-physical systems security.

-Thorough exploration of threat detection and prevention techniques.

-Application-focused chapters covering smart grid, healthcare, and more.

-Integration of game theory and augmented reality in cyber-physical systems.

-Comprehensive overview on network and computer forensic frameworks.

DFT-Based Studies On Atomic Clusters explores the structures, properties, and applications of a variety of atomic clusters using density functional theory (DFT) methods to offer a simple and comprehensive explanation of the subject.

The book is organized into seven chapters. Chapter 1 introduces atomic clusters and provides a quick survey of density functional theory and its role in the study of atomic clusters. Chapter 2 discusses the optimization of atomic clusters using various algorithms. Chapters 3, 4, and 5 cover the applications of DFT methods on chemical interactions involving metal complexes and ions. Chapter 6 is devoted exclusively to molecular clusters for completeness. Chapter 7 concludes the book and provides a perspective on future directions on the subject.

Theoretical and practical concepts of DFT methods of the book are systematically and concisely presented with the help of clear language. Several illustrations in the form of graphics and tables are included for the benefit of readers.

This reference is intended as a guide for advanced graduate and doctorate level scholars, postdoctoral researchers, and faculty members who are required to understand the application of density functional theory for explaining the properties of atomic clusters as part of foundational coursework or supplementary reading.

Data Science for Agricultural Innovation and Productivity explores the transformation of agriculture through data-driven practices. This comprehensive book delves into the intersection of data science and farming, offering insights into the potential of big data analytics, machine learning, and IoT integration. Readers will find a wide range of topics covered in 10 chapters, including smart farming, AI applications, hydroponics, and robotics. Expert contributors, including researchers, practitioners, and academics in the fields of data science and agriculture, share their knowledge to provide readers with up-to-date insights and practical applications. The interdisciplinary emphasis of the book gives a well-rounded view of the subject. With real-world examples and case studies, this book demonstrates how data science is being successfully applied in agriculture, inspiring readers to explore new possibilities and contribute to the ongoing transformation of the agricultural sector. Sustainability and future outlook are the key themes, as the book explores how data science can promote environmentally conscious agricultural practices while addressing global food security concerns. Key Features: - Focus on data-driven agricultural practices - Comprehensive coverage of modern farming topics with an interdisciplinary perspective - Expert insights - Sustainability and future outlook -Highlights practical applications Data Science for Agricultural Innovation and Productivity is an essential resource for researchers, data scientists, farmers, agricultural technologists, students, educators, and anyone with an interest in the future of farming through data-driven agriculture.

This book is a detailed reference guide on deep learning and its applications. It aims to provide a basic understanding of deep learning and its different architectures that are applied to process images, speech, and natural language. It explains basic concepts and many modern use cases through fifteen chapters contributed by computer science academics and researchers. By the end of the book, the reader will become familiar with different deep learning approaches and models, and understand how to implement various deep learning algorithms using multiple frameworks and libraries. The second part is dedicated to sentiment analysis using deep learning and machine learning techniques. This book section covers the experimentation and application of deep learning techniques and architectures in real-world applications. It details the salient approaches, issues, and challenges in building ethically aligned machines. An approach inspired by traditional Eastern thought and wisdom is also presented. The final part covers artificial intelligence approaches used to explain the machine learning models that enhance transparency for the benefit of users. A review and detailed description of the use of knowledge graphs in generating explanations for black-box recommender systems and a review of ethical system design and a model for sustainable education is included in this section. An additional chapter demonstrates how a semi-supervised machine-learning technique can be used for cryptocurrency portfolio management. The book is a timely reference for academicians, professionals, researchers and students at engineering and medical institutions working on artificial intelligence applications.

This book is an essential guide to analysis and design of tall buildings and foundations. The book covers the basic consideration of tall buildings, selection of a suitable structural form, structural materials, and analytical methods for several types of construction loadings. The last chapter of this book presents an illustrated case study for learners. An appendix of different structural analysis calculations rounds up the book. The detailed analysis and learning material presented in the book is intended to enable readers to master the basics and understand how to execute practical civil engineering projects.

Key features:

- Covers the essentials of skyscraper design and construction in detail with a focus on learning.

- Covers building modelling parameters and criteria with design reports and computer inputs.

- Includes analysis and notes for foundation layout, loadings and the excavation and lateral support system (ELS).

- Includes more than 250 detailed illustrations of concepts, construction plans and photos from real projects.

- Includes references and appendices for advanced readers.

- Includes more details than most of the similar texts, with practical guidelines based on references from many buildings and foundation projects.

The authors have extensive research and practical experience of buildings and foundation analysis and design in Hong Kong, and have actively served as regional engineering committee members overseeing structural and foundation disciplines.

Diagnosis and Management of Fetal Disorders reviews key points in obstetrics/maternal fetal medicine imagery analysis of the pregnant uterus and its contents. Specifically, chapters cover ultrasound of different fetal organs, physiological systems and diseases. The authors also provide radiological correlation to help the obstetrician, pediatrician, radiologist, and other specialists know the basics and some more advanced concepts that will allow diagnosis of fetal abnormality, and what those findings mean to the patient and their families vis-a-vis the fetus in their pregnancy. It is ,therefore, a handbook that helps medical residents and professionals to assess cases in real-time or to review a given clinical problem. Key Features - 13 structured chapters covering key topics related to the ultrasound of different fetal organs, physiological systems and diseases - Evidence-based presentation through detailed images and references - Portability and practical information on general and differential diagnostics to consider in fetal and uterine examinations. - Useful information for medical and genetic counseling affected mothers and couples The book is intended for a broad readership in medicine including medical students, specialty trainees and attending physicians in obstetrics, pediatrics, radiology, and subspecialty trainees in maternal fetal medicine, neonatology, ultrasound imaging. Medical professionals in allied fields including sonography, family practice, and genetic counseling will also benefit from the information presented in the book.

This 3 volume set offers a comprehensive compilation which presents detailed information about ophthalmic (retinal, vitreous and macular) diseases. Key features of this set include:

o Emphasis on practical features of clinical diagnosis

o Concise and didactic presentation of key manifestations of diseases designed for rapid reference and target recall

o A vast selection of illustrations to sharpen clinical problem-solving skills

o Step by step treatment approaches to enhance the reader's ability to handle medical cases

o Citations or relevant research articles in each chapter for further reading

The second volume of this set covers several choroid and retinal disorders including, commotio retinae, choroidal rupture and macular trauma, retinal breaks and detachment, and a variety of congenital / genetic eye diseases such as Best’s disease and Stargardt disease. Written by a group of retina specialists, this book is an excellent resource for knowledge about retinal disorders. The streamlined format and evidence based medicine presented in the volume make this book the perfect reference for medical students, residents, general ophthalmologists and retina specialists.

Differential and Integral Calculus - Theory and Cases is a complete textbook designed to cover basic calculus at introductory college and undergraduate levels. Chapters provide information about calculus fundamentals and concepts including real numbers, series, functions, limits, continuity, differentiation, antidifferentiation (integration) and sequences. Readers will find a concise and clear study of calculus topics, giving them a solid foundation of mathematical analysis using calculus. The knowledge and concepts presented in this book will equip students with the knowledge to immediately practice the learned calculus theory in practical situations encountered at advanced levels.

Key Features:

- Complete coverage of basic calculus, including differentiation and integration

- Easy to read presentation suitable for students

- Information about functions and maps

- Case studies and exercises for practical learning, with solutions

- Case studies and exercises for practical learning, with solutions

- References for further reading

This reference reviews the architectural requirements of IT systems that are designed to digitally transform business operations. It is a compilation of 7 timely reviews that demonstrate how adopting emerging technologies and examining the security-based concerns can lead to innovation in the business sector. The aim of the book is to guide scholars and business consultants on IT and business frameworks that can help new and existing organizations navigate the challenges posed by disruptive technologies to create a competitive advantage. The reviews are contributed by experts in business and information technology.

The chapters cover diverse topics related to technological advancements and digital security measures. Chapter 1 offers insights into accessing and securing patient medical records through a blockchain-based framework, detailing research methodology, scalability, and standards. Chapter 2 discusses cyber threats in IoT-connected cars, addressing vulnerabilities, attack methods, and defense strategies. Chapter 3 focuses on malware analysis and detection using machine learning techniques. Chapter 4 emphasizes on securing IoT-based home automation. Chapter 5 presents an IoT policy and governance reference architecture to ensure integrity and security across devices. Chapter 6 explores organizational security improvements to prevent deepfake ransomware. Finally, Chapter 7 examines the use of machine learning in credit card fraud detection, discussing challenges and control layers.

This book is a comprehensive review of technologies and data in healthcare services. It features a compilation of 10 chapters that inform readers about the recent research and developments in this field. Each chapter focuses on a specific aspect of healthcare services, highlighting the potential impact of technology on enhancing practices and outcomes.

The main features of the book include 1) referenced contributions from healthcare and data analytics experts, 2) a broad range of topics that cover healthcare services, and 3) demonstration of deep learning techniques for specific diseases.

Key topics:

- Federated learning in analysis of sensitive healthcare data while preserving privacy and security.

- Artificial intelligence for 3-D bone image reconstruction.

- Detection of disease severity and creating personalized treatment plans using machine learning and software tools

- Case studies for disease detection methods for different disease and conditions, including dementia, asthma, eye diseases

- Brain-computer interfaces

- Data mining for standardized electronic health records

- Data collection, management, and analysis in epidemiological research

The book is a resource for learners and professionals in healthcare service training programs and health administration departments.

Diverse Strategies for Catalytic Reactions is a compelling exploration of catalysis, a cornerstone in chemical sciences that has propelled the evolution of chemical manufacturing at the industrial scale.

Highlighting the distinctive characteristics of catalysis, the book delves into pivotal topics and subfields. It underscores the revolutionary role catalysis plays in novel design, synthesis, and energy-efficient development, while minimizing side products, promoting atom economy, and embracing green chemistry principles. The comprehensive contents of this book include an array of chapters by experts, each addressing a specific catalytic approach, such as recent advances in electrocatalysis, nano-catalysis for selective oxidation, micellar catalysis, green catalysts, and more. Each of the 7 book chapters includes a summary and list of references for a broad range of readers. Readers will understand the range of chemical engineering strategies that are used to speed up reactions and synthesize molecules of interest. With its rich insights and practical applications, this book serves as an invaluable reference for graduate students, researchers, and professionals across academic and industrial domains.

Drug Addiction Mechanisms in the Brain explores the fascinating world of drug substances and their effects on the brain. This book provides a comprehensive overview of the ten major substances that contribute to drug addiction Information about each substance is presented in a specific chapter, shedding light on their biochemical mechanisms and physiological effects. From the stimulating effects of cocaine to the sedative properties of heroin, and the hallucinogenic experiences induced by LSD, the book takes the reader through the intricate pathways of addiction. Other substances covered in the book include alcohol, nicotine, MDMA, METH, morphine, ketamine, and fentanyl. Readers will gain an understanding about neurochemical alterations in the brain Anyone looking for interesting knowledge about the addictive nature of common drugs and their complex interplay with the brain will find this book informative.

Drug Metabolism and Bioanalysis Letters publishes letters, original research articles, mini-reviews, thematic issues based on mini-reviews and letters, commentaries, technical notes and drug clinical trial studies on major advances in all areas of drug metabolism and bioanalysis.

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation; recent developments for the identification of drug metabolites, reactive intermediate and glutathione conjugates. LC/MS and other key detection methods, including ligand binding assays, sample preparation, chromatography and separation sciences, method development and validation with applications in drug and metabolite assays, pharmacokinetic/toxicokinetic assays, biomarker assays, immunogenicity assays, diagnostic assays.

This book covers some recent researches on the interface between drug misuse and crime and demonstrates that some types of violent crimes are more intimately related to alcohol and / or drug consumption. It is written for researchers, health and law professionals engaged in the evaluation, management and treatment of different types of offenders. It is organized by a number of phenomena that are known (or supposed) to link drugs and crime. This book shows that the application of punishment under the guise of deterrence, despite its ineffectiveness, is frequently preferred to a more adequate management for some types of offenders. This book provides ten manuscripts that describe different aspects of the relationship between drugs and crimes, always focusing on Brazilian reality. It shows that a partnership between specialized mental health professionals, lawyers and policy makers is urgent with respect to this subject in Brazil and other countries.

A biosensor is an integrated receptor-transducer device that converts a biological response into an electrical signal. The design and development of biosensors have taken center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications in healthcare and disease diagnosis, environmental monitoring, water and food quality, and drug delivery. Due to their adaptability, ease of use in relatively complex samples, and portability, the significance of electrochemical biosensors in analytical chemistry has increased manifold. Electrochemistry has been pivotal in developing transduction methods for biological processes and biosensors. In parallel, the explosion of activity in nanoscience and nanotechnology and their huge success have profoundly affected biosensor technology, opening new avenues of research for electrode materials and transduction.

Electrochemical Biosensors in Practice: Material and Methods particularly explores the use of silver and gold nanoparticles for signal amplification, photocurrent transduction, and aptamer design. Therefore, the book serves as an introductory text for those specializing in biosensors and bioelectronics and their practical applications.

Key features

Includes structured information for easy understanding of the subject

Provides an introduction to biosensors and electrochemical biosensor classification

Explains fundamental concepts and practical electrochemistry techniques for research

Provides notes on essential electrochemical sensor materials such as graphene, carbon nanotubes, conductive polymers, and other advanced materials

Provides information about electrochemical biosensor development

Informs readers about recent applications and research findings

Includes references for further reading

This reference provides an update on current therapies to treat neglected diseases, a class of diseases that primarily affect tropical regions where investment in research and development is limited.

The book starts with an introduction to neglected diseases followed by reviews of therapeutic strategies to overcome the impact of neglected diseases. This is followed by updated information for handling leprosy, dengue, lymphatic filariasis, dracunculiasis, helminthiasis, Chagas’ disease, neurocysticercosis, leishmaniasis, rabies, trematodiasis, buruli ulcer and trachoma in 10 focused chapters, respectively. The chapters provide information on disease mechanism, transmission and management protocols, along with scientific references. The book serves as a resource for healthcare professionals, and scholars who need a detailed understanding of these infectious diseases.

This reference distills information about emerging technologies and applications for smart city design and sustainable urban planning. Chapters present technology use-cases that have radical novelty and high scalability with a prominent impact on community living standards. These technologies prepare urban and rural dwellings for the transformation to the smart world.

Applications and techniques highlighted in the book use a combination of artificial intelligence and IoT technologies in areas like transportation, energy, healthcare, education, governance, and manufacturing, to name a few.

The book serves as a learning resource for smart city design and sustainable infrastructure planning. Scholars and professionals who are interested in understanding ways for transforming communities into smart communities can also benefit from the cases presented in the book.

Cultivators and livestock farmers are increasingly arranging innovative technical and scientific estimations with the aim to enhance agricultural sustainability, effectiveness, and plant health. Innovative farming technologies incorporate biology with smart technology (computers and sensor devices) exchanging information with one another autonomously in a structured farm management system.

This book presents reviews on innovative techniques and methodologies to complement conventional plant control and breeding attempts toward enhancing crop yield and production. Reviews covered in this volume include:

-Active compounds from pomegranate seeds

-Application of Enterococci and their bacteriocins for meat biopreservation

-Technological advancement in the detection and identification of plant pathogens

-Machine learning for precision agriculture

-Use of remote sensing technology and geographic information systems for agriculture and

environmental observation

The information presented in this volume will provide helpful updates for students, technology experts and professionals in the food security and sustainable agriculture sectors.

This book examines a wide range of emerging sources off water pollution. It consists of thirteen chapters dedicated to the topic, giving readers comprehensive information about the types of materials involved and the solution for their removal.

The first five chapters present an analysis of the emerging water pollutants, their toxicities, legislations available to monitor and regulate their emissions. This introduction is followed by 3 chapters that cover risk assessment of emerging pollutants, their fate and life cycle assessment. The last section of the book goes through the details of remediation technologies for wastewater treatment.

This reference is equally suitable for academia, industry professionals and students, presenting state-of-the-art learnings on emerging water pollutants and their remediation methods.

Environmental Law in the Russian Federation presents a comprehensive textbook on the current state of environmental legislation of the Russian Federation. The textbook is divided into three sections that are ordered for an increasing level of specialization in the subject.

- The first section (General Part) gives a definition of environmental law, formulates its principles and considers the sources of environmental law and legal relations. Readers will learn about the issues related to the ownership of natural resources, the legal framework and specifics of environmental protection and management, and associated human and civil rights. The distinguishing features of economic regulation in the area of environmental protection as well as issues of responsibility for environmental offenses are also covered.

- The second section (Special Part) sets forth the main environmental requirements for certain types of economic and other human activities and the specifics of environmental protection in areas with a special environmental legal regime (specially protected areas and ecological disaster zones). Chapters in this section consider the main areas of protection of certain natural objects (water, forests, land, etc.).

- The third section (Specialized Part) clarifies the main areas of international cooperation in the field of environmental protection and considers the main characteristics of the environmental protection experience of other countries.

The textbook is an essential reference for law and business students in Russian schools. It is also of interest to entrepreneurs planning ventures in Russia and researchers involved in comparative legal analysis.