Bentham Science Publishers

This book explores cutting-edge biocarbon polymer composites. The book brings together nine edited chapters that explore the development, properties, and applications of these eco-friendly materials, highlighting their potential to transform industries and reduce the environmental impact of traditional polymers. Spanning a range of critical topics, this book begins with an introduction to biocarbon and polymer materials, providing a solid foundation. It then progresses into the latest research on biocarbon sources, processing techniques, and characterization methods. Subsequent chapters cover the mechanical, thermal, and electrical properties of biocarbon polymer composites, along with their applications in diverse industries such as automotive, construction, and packaging. Contributors highlight real-world case studies and examples to showcase the practical relevance of these materials.

Readers will gain a comprehensive understanding of the science and technology behind biocarbon polymer composites, enabling them to make informed decisions in materials selection and development. In an era of increasing environmental consciousness, this book emphasizes the eco-friendly nature of biocarbon composites, offering sustainable alternatives to traditional plastics. Additionally, this book bridges the information gaps between different disciplines and it is intended for a wide range of readers, from materials scientists and engineers to environmentalists and industry policymakers.

Bioceramics: Status in Tissue Engineering and Regenerative Medicine (Part 2) presents recent advancements in biocompatible ceramics and bioactive glasses, emphasizing their expanding applications in hard and soft tissue engineering. This book explores innovative manufacturing techniques like 3D printing and additive manufacturing and examines the therapeutic potential of bioceramics in areas such as bone regeneration, microbial infection management, wound healing, and cancer treatment. It also discusses current challenges, clinical applications, and future research directions. This book is a valuable resource for those developing biocompatible materials for medical applications.

Key Features:

- Comprehensive overview of bioceramic and bioactive glass applications in tissue engineering.

- In-depth analysis of manufacturing techniques, including 3D printing and additive manufacturing.

- Insights into clinical challenges, preclinical assessments, and future perspectives in regenerative medicine.

Aluminium is a chemical element present in earth’s crust and it is a known environmental toxin which has been found to be associated with various neurological disorders. Aluminium has been found to be a very strong risk factor for the development of Alzheimer’s disease.

Biochemical Mechanisms of Aluminium Induced Neurological Disorders explains the association of aluminium with neurological disorders. The book introduces the reader to sources of aluminium exposure, followed by an explanation of pharmacokinetics of aluminium and the different biochemical pathways that cause neurological effects. Chapters cover the typical mechanisms associated with aluminium neurotoxicity such as synaptic impairment as well as recent topics of interest such as the role of aluminum in impairing blood-brain barrier functions. Separate chapters which cover clinical evidence of aluminium toxicity and its management are also included in the book.

Biochemical Mechanisms of Aluminium Induced Neurological Disorders is a concise, yet informative reference on the subject of aluminium neurotoxicity for all readers, whether they are students of biochemistry, pharmacology and toxicology, clinical neurologists, environmentalists interested in metal pollution or general readers who want to learn about the toxic effects of aluminium in humans.

This book is a concise textbook of iatrogenic pathology. Chapters cover iatrogenesis relevant to a broad range of medical subspecialties (cardiology, gastroenterology, gynecology, neurology, endocrinology and much more). The book presents an introduction to iatrogenesis which is followed by chapter-wise descriptions of iatrogenic lesions (lesions due to adverse drug reactions, lesions occurring during diagnosis and consequences of various therapeutic interventions) of the organs and systems of the body.

This textbook is a handy resource on iatrogenic pathology for medical students and working professionals (clinical and nursing staff) involved in a range of medical subspecialties

Naturally-derived biomaterials invite immense interest from diverse segments of science and engineering. Recent decades have witnessed a leap in knowledge and efforts in ongoing research with biomaterials as synthons, yet biomaterial research never fails to create surprises. This book summarizes modern knowledge of bioderived materials for beginners in research and advanced readers in materials science.

The book lays the foundations of understanding the design and development of mimetic peptides and enzyme mimetic bioinorganic catalysts, including the toolsets used in the process. Next, the book demonstrates different approaches for obtaining task-specific designer hydrogels. Additional topics covered in the book are tissue engineering and regenerative medicine. From this point, the book presents information on complex biomaterials systems: bacterial cellulose, cell membrane architecture for nanocomposite material design, and whole cellular microorganisms. Chapters provide applied knowledge with information on the strategies used to design novel biomaterials for applications such as drug delivery, therapy and controlled chemical synthesis.

In summary, this book brings together a wealth of information on bioderived materials with versatile applications, derived from different sources, such as plant derivatives and microorganisms (in part or whole as synthons), benefitting readers from multidisciplinary backgrounds.

This brief book is dedicated to the quantitative analyses and systematic discussion of spatial biodiversity and biogeographic patterns in the Asia‐pacific region comprised of China, India and adjacent countries. The book is split into two sections. The first section presents readers with detailed statistical methods to conduct spatial macro‐biodiversity and biogeography analyses. Step-by-step instructions on how to perform these statistical methods by using the statistical program R are also provided. In the second part, different quantitative case studies are presented covering several topics, including phylogenetics, spatial statistics, multivariate statistics and ecological genomics. Each case study concludes with a detailed interpretation of the quantitative results and how these results are relevant to local and regional ecological processes. This reference is suitable for academics interested in biostatistics biodiversity and ecological studies specific to the Asia Pacific region and China.

Bioencapsulation (or microencapsulation) of cells and their implantation into a body of immunoprotected cells allows researchers to revive a missing or defective function in the cells. Microencapsulated cells have reached the clinic where they have been shown to be safe and efficacious in numerous clinical trials. Cell types that have been encapsulated for therapeutic purposes include hybridomas, islet cells, "platform" cell lines e.g. HEK293 and CHO cells as well as an increasing focus on the encapsulation of stem cells. This e-book explains the different methods used for achieving cell bioencapsulation based on different polymers e.g. alginate, cellulose sulphate and agarose. Other chapters in this book subsequently describe the use of cell encapsulation in cancer therapy to improve on existing chemotherapies by reducing doses and thus side effects while increasing efficacy for long term in vivo production of (i) tumoricidal or virus neutralising antibodies, (ii) insulin to achieve a self regulating treatment for diabetes and (iii) neuron nurturing factors to treat CNS diseases such as epilepsy, disorders like Parkinson's disease, Alzheimer, Amyotrophic lateral sclerosis, Huntington's disease and pathologies caused by trauma and/or ischemic processes. The book also includes a chapter reviewing the genetic engineering of cells to allow controlled production of biotherapeutics from encapsulated cells.

This is a unique and timely book which brings together contributions from some of the leading researchers in the field of cell encapsulation. Interested readers are provided an overview of the exciting developments and clinical experiences of researchers with cell bioencapsulation.

The exponential increase in computing power in the late twentieth century has allowed researchers to gather, process and analyze large volumes of information and construct rational paradigms of systems. Life sciences are no exception and computing advances have led to the birth of fields such as functional genomics and bioinformatics and facilitated an expansion of our understanding of biological systems. Biological Systems: Complexity and Artificial Life is an essential primer on systems biology for biologists and researchers having a multidisciplinary background. The volume covers a variety of theoretical models explaining biological processes. The book starts with an introductory chapter on the classical molecular biology paradigm and progresses towards concepts related to enzyme kinetics, non equilibrium dynamics, cellular thermodynamics, molecular motion in cells and more. The book concludes with a philosophical note on the concept of the biological system.

Both Asia and Africa are home to many plants that can be used for the treatment of many diseases and their medicinal properties are gaining interest in western societies. Medicinal plants from Asia and Africa are used for their healing abilities and also have a symbolic meaning in communities.

The importance of traditional autochthonous plant remedies plays a crucial role in the health of millions of people of these two continents. Even today, traditional medicine represents the dominant medical system for millions of people showing a significant impact on health care practices. Therefore, traditional operators still represent a vital part of regional healthcare systems. For this reason, pharmaceutical industries consider traditional medicine as a source for the identification of bioactive compounds that can be used in the preparation of synthetic drugs.

Biologically Active Natural Products from Asia and Africa: A Selection of Topics guides the reader to information about new natural products from these regions and the different ways to use them to treat or alleviate many of the most common diseases. The volume presents nine topics covering a number of facets of natural product medicine including:

- pharmaceutical analysis of anti-diabetic herbal medicines from Bangladesh and local retailers

- caffeine intake and the risk of female infertility

- pharmaceutical analysis of Urena sinuata (bur mallow)

- anti-CHIKV activities of diterpenes and their derivatives

- anti-inflammatory nanogel for the treatment of psoriasis

- antlithiatic properties of Moroccan medicinal plants

- ethnobotanic, phytochemical and biological activities of Aristolochia longa L. (pipevine)

- wound healing potential of combined extracts of stem bark and leaves of sphenocentrum jollyanum (an African shrub)

This is a handy reference for specialists and R&D experts in pharmaceutical chemistry who wish to be informed about current knowledge on developing natural remedies in Asia and Africa

Bioluminescence, the cold living light or the cold fire of the sea is extremely common in all oceans at all depths. However, this phenomenon is nearly absent in freshwater, with the exception of a freshwater limpet. More than 75% of deep-sea creatures have been reported to produce their own light. The luminescent marine plankton such as dinoflagellate, radiolarians, jellyfish, comb jellies, annelids, copepods, ostracods, mysids, amphipods, euphausiids, and tunicates form an important component in the marine food chain. Research on luminescent marine plankton is gaining momentum owing to its importance in life science research and medicine. The glowing Green Fluorescent Protein (GFP) extracted from the North Pacific jellyfish, Aqueorea victoria (for which the Japanese biologist, Osamu Shimonmura won the Nobel Prize in Chemistry in 2008) has helped shed light on key processes such as the spread of cancer, the development of brain cells, the growth of bacteria, damage to cells by Alzheimer's disease, and the development of insulin-producing cells in the pancreas. Therefore, it is difficult to underscore the importance of bioluminescence and the organisms associated with this phenomenon.

Bioluminescent Marine Plankton is a unique reference that attempts to provide answers to questions about bioluminescence. The first of its kind, this book attempts to answer questions on the subject with a focus on planktonic organisms. 12 chapters provide information about the chemistry of bioluminescence, types of bioluminescent displays, distribution of bioluminescence among marine plankton, ecological functions and utility of planktonic bioluminescence. Chapters are dedicated to the biology and ecology of specific groups of plankton that span about 200 luminescent marine species.

The detailed book is an essential compendium on marine plankton for a broad range of readers who want to learn about bioluminescent plankton. A list of detailed references is also provided for the benefit of teachers, students, researchers and enthusiasts interested in marine biology, aquaculture, and environmental sciences.

This reference is a guide to biomaterial fabrication techniques. The book comprises ten chapters introducing the reader to a range of biomaterial synthesis while highlighting biomedical applications. Each chapter presents a review of the topic followed by updated information about relevant core and applied concepts in an easy to understand format. The first two chapters present vital information about biomaterial components, such as polymer nanocomposites and scaffolds, and the strategies used for their fabrication. The proceeding chapters explain the principles of the most widely used fabrication techniques, and their application in detail. These include freeze drying, electrospinning, 3D printing, multiphoton lithography, particulate leaching, supramolecular self assembly, solvent casting and melt molding. The book is an essential primer on biomaterial synthesis for students and early career researchers in the field of biomedical engineering, applied chemistry and tissue engineering.

Biomedical Applications of Perovskites: The Era of Bio-Piezoelectric Systems focuses on recent developments in the area of piezoelectric systems and their biomedical applications. A compilation of 19 edited chapters covers different piezoelectric materials, device designs, and their use cases. Readers will be familiarized with the many perovskite materials being used in research and development as well as the role they play in designing novel medical devices and biomaterials.

Key Features

- systematically explains the piezoelectric perovskite materials starting from their introduction, their structure and synthesis techniques

- explains the key materials used in devices such as pacemakers and nanogenerators

- highlights a range of applications including bone regeneration and growth, bone replacement, tissue engineering, dental science, neurotrauma and neurodegenerative disease treatment and bionic prosthesis

- discusses future challenges and the roadmap for piezoelectric perovskite materials

- Presents scientific references for advanced reading

The biophysics of diving and decompression in the human body are complex. The average individual experiences atmospheric pressure swings of 3% at sea level and over 20% at altitudes greater than a mile. Divers and their equipment can experience compressions and decompressions in orders of greater magnitude than pressures outside water, all within considerably shorter time spans. The understanding of the mechanics behind diving is based on absolute pressure and pressure changes. While these mechanics are readily quantified in physics, chemistry, and engineering applications, the physiological and medical aspects of pressure changes in living systems need to be understood clearly to assess the safety of routine divers.

This monograph is a compilation of a body of knowledge on biophysics, gas transport, bubble studies and physiological models used for diving and hyperbaric applications. Information in the monograph is divided into three parts that cover biophysics and models, data correlation and validation approaches and practical applications, respectively. The book is a useful resource for researchers and maritime professionals who wish to understand the biophysics behind underwater diving and decompression for the purpose of maritime operations as well as diving simulation applications.

Bio-based polymers are materials that are produced from renewable resources. Their biodegradable properties are the driver of worldwide interest among researchers and manufacturers in recent years due to the demand and need for alternatives to fossil fuel based polymers. The use of biodegradable polymers creates a sustainable industry. In contrast, the raw materials for synthetic polymers derived from petrochemicals will eventually deplete and most of them are non-biodegradable. Despite these advantages, bio-based polymers account for only a tiny fraction of the total global plastic market.

Non-biodegradability issues of synthetic pharmaceutical inactive ingredients strongly emphasized innovators towards the development of biopolymers. Recently natural biodegradable excipients gained significant attention due to their sustainability and engineered applications. Innovative technologies to transform these materials into value-added chemicals via novel graft-polymerization or co-processing techniques for the production of high-performance multifunctional and low-cost polymers with tunable structures are key parts of its sustainable development.

Biopolymers Towards Green and Sustainable Development elaborates on important issues that surround bio-based polymers. It gives the reader an overview of biopolymers, the impact of non-biodegradable polymers on the environment and health, emerging sources of biodegradable polymers, structural and morphological characterization techniques, thermomechanical properties, biodegradable plastics from biopolymers, pharmaceutical, biomedical, and textile applications, and pharmacokinetics and pharmacodynamics. with a brief on bibliometric. Moreover, a brief bibliometric meta-analysis on bio-based pharmaceutical excipients provides an update about teams involved in the development of polymeric research that may be of interest to anyone who wants to work on sustainable biopolymer projects.

Key Features

- provides an updated summary on recently discovered natural polymeric materials

- gives a thorough breakdown of the vast range of biopolymer applications including fabrication of conventional and novel drug delivery, polymeric scaffolds, composites, microneedles, and green synthesis of metallic nanoparticles,

-summarizes pharmacology and pharmacokinetics of the inactive pharmaceutical ingredient and excipients

- presents a bibliometric meta-analysis indicating potential collaboration between country, organization, institution, and authors with a view on recent ongoing trends with biopolymers.

Increased industrial and agricultural activity has led to the contamination of the earth's soil and groundwater resources with hazardous chemicals. The presence of heavy metals, dyes, fluorides, dissolved solids, and many other pollutants used in industry and agriculture are responsible for hazardous levels of water pollution. The removal of these pollutants in water resources is challenging. Bioremediation is a new technique that employs living organisms, usually bacteria and fungi, to remove pollutants from soil and water, preferably in situ. This approach is more cost-effective than traditional techniques, such as incineration of soils and carbon filtration of water. It requires understanding how organisms consume and transform polluting chemicals, survive in polluted environments, and how they should be employed in the field.

Bioremediation for Environmental Pollutants discusses the latest research in green chemistry and practices and principles involved in quality improvement of water by remediation. It covers different aspects of environmental problems and their remedies with up-to-date developments in the field of bioremediation of industrial/environmental pollutants. Volume 1 focuses on the bioremediation of heavy metals, pesticides, textile dyes removal, petroleum hydrocarbon, microplastics and plastics.

Waste management is one of the major challenges for environmental and public health organizations for maintaining safety standards in any area. Population growth and urbanization increase the difficulty in maintaining a sustainable waste management system. Bioremediation refers to the use of living organisms in processes designed to remove toxic chemicals present in waste material. Bioremediation represents a sustainable way to remove a range of environmental pollutants.

Bioremediation: Challenges and Advancements covers the subject of bioremediation in eight chapters that focus on a broad range of waste sources, their adverse impacts on the ecosystem, and the advanced strategies for their remediation. Each chapter also highlights the problems encountered in bioremediation processes.

Key features:

- Comprehensive coverage of bioremediation in 8 reader-friendly chapters

- Highlights methods and challenges of bioremediation in one volume.

- Introduces the reader to bioremediation

- Explains recent biotechnological methods for removing heavy metals and xenobiotic compounds

- Describes strategies including physical, chemical, and biological methods to mitigate radioactive waste from contaminated sites and water bodies

- Details the use of microbial-aided remediation techniques for the management of biomedical and electronic wastes, and its impact on the ecosystem

- Describes bioremediation technologies for decontamination of solid waste pollutants

- Showcases the application of Omics approaches such as genomics, transcriptomics, proteomics, and metabolomics to improve bioremediation processes.

- Covers bioremediation of agro-wastes

- Includes detailed references

This book is an informative reference for scholars (researchers, undergraduate and graduate students of environmental sciences, microbiology and biotechnology) professionals (environmental engineers) and researchers, giving each a good understanding of the significance of bioremediation in solid waste management and the restoration of contaminated sites.

Increasing public health concern about healthy lifestyles has sparked a greater demand among consumers for healthy foods. Natural ingredients and environmental friendly food production and processing chains are more aligned to meeting the demand for healthy food. There is a wide array of food additives and chemicals that have nutritional value. The biotechnological food production processes, therefore, vary for different types of food chemicals and ingredients accordingly.

Biotechnological Production of Natural Ingredients for Food Industry explains the main aspects of the production of food ingredients from biotechnological sources. The book features 12 chapters which cover the processes for producing and adding a broad variety of food additives and natural products, such as sweeteners, amino acids, nucleotides, organic acids, vitamins, nutraceuticals, aromatic (pleasant smelling) compounds, colorants, edible oils, hydrocolloids, antimicrobial compounds, biosurfactants and food enzymes.

Biotechnological Production of Natural Ingredients for Food Industry is a definitive reference for students, scientists, researchers and professionals seeking to understand the biotechnology of food additives and functional food products, particularly those involved in courses or activities in the fields of food science and technology, food chemistry, food biotechnology, food engineering, bioprocess engineering, biotechnology, applied microbiology and nutrition.

Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease.

Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology.

Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource.

This reference presents information about different facets of IoT and blockchain systems that have been recently proposed for practical situations. Chapters provide knowledge about how these technologies are applied in functions related to trust management, identity management, security threats, access control and privacy.

Key Features:

- Introduces the reader to fundamental concepts of IoT and blockchain technology

- reports advances in the field of IoT, ubiquitous computing and blockchain computing

- includes the applications of different frameworks

- explains the role of blockchains in improving IT security

- provides examples of smart grids, data transmission models, digital business platforms, agronomics and big data solutions

- Includes references for further reading

Blockchain Applications for Secure IoT Frameworks: Technologies Shaping the Future is a handy reference for information technology professionals and students who want updated information about applications of IoT and blockchains in secure operational and business processes.

This volume reviews cutting-edge innovations in blockchain technology that are propelling the healthcare industry into a new era of efficiency and security. It brings 14 reviews contributed by experts in blockchain and Web3 technologies into a single volume. Each contribution includes a summary for easy understanding and scientific references for advanced readers.

Key Themes:

Empowering Decentralized Healthcare: Learn about the future of decentralized healthcare, powered by blockchain, ensuring a seamless and patient-centric experience.

Clinical Trials: Discover how blockchain is reshaping clinical trials, offering a glimpse into a future of optimized medical research.

Data Security: Uncover the strategic use of blockchain in securing vital clinical trials data, ensuring confidentiality and integrity at every step.

Blockchain-based Healthcare delivery: Delve into a comprehensive review of blockchain technology in the health sector, revealing its potential to transform healthcare systems with

Predict, Prevent, and Protect: Understand how blockchain technology serves as a predictive tool, aiding in the prevention and control of the spread of COVID-19.

This volume is a must-read for healthcare practitioners and administrators seeking to harness the power of blockchain in medicine and healthcare. It also provides information for researchers and business professionals who want to understand the innovative role of blockchain technology in the healthcare sector.

Blockchain-Enabled Internet of Things Applications in Healthcare: Current Practices and Future Directions examines cutting-edge applications, from blockchain-powered IoT innovations in healthcare systems to intelligent health profile management, remote patient monitoring, and healthcare credential verification. Additionally, the book extends its insights into blockchain-enabled IoT applications in smart agriculture, highlighting AI-driven technologies for health management and sustainable practices.

With expert analyses, case studies, and practical guidance, this book offers readers a roadmap for implementing these technologies to improve efficiency, security, and data management in healthcare. It is an invaluable resource for industry professionals, researchers, and students interested in the future of healthcare technology.

Key Features:

- Exploration of blockchain and IoT applications in healthcare and agriculture

- In-depth case studies and expert analyses

- Practical insights into technology challenges and benefits

Body contouring is a rapidly growing field within plastic surgery. Safe and effective techniques have been developed in recent times with increased patient satisfaction indicated by visual analogue scores.

This book brings together contributions from leading experts in bariatric surgery from all across the globe. The body contouring techniques and procedures described in the book have been developed specifically to treat massive weight loss patients in contrast to traditional methods that are normally unsuitable for such patients. These procedures focus on maximizing the removal of excess and unwanted skin whilst preserving volume and restoring contour. The key issue of patient safety is also addressed in the book.

Body Contouring Following Bariatric Surgery and Massive Weight Loss should be a useful resource for surgeons and clinicians interested in massive weight loss surgery and satisfactory visual analogue scores.

This reference book explains the fundamentals of Bose Einstein Condensation (BEC) in excitons and polaritons. It presents five chapters exploring fundamental concepts and recent developments on the subject. Starting with a historical overview of BEC, the book progresses into the origins and behaviors of excitons and polaritons. Chapters also cover the unique thermalization and relaxation kinetics of excitons, and the distinctive features of polaritons, such as lasing, superfluidity, and quantized vortices.

The chapters dedicated to BEC in excitons and polaritons detail experimental techniques, theoretical modeling, recent advancements, and practical applications in a simplified way for beginners. This book serves as a resource for researchers, physicists, and students interested in the phenomena of BEC, providing insights into both the theoretical foundations and the practical implications of excitons and polaritons.

The mathematical modelling of free and moving boundary problems are an important topic in engineering, industry, technology and theoretical sciences. These models allow us to make calculations involved in phase change transitions of materials due to heat transfer.

Boundary layer applications are widespread in research and industry. Boundary Element Methods for Heat Transfer with Phase Change Problems: Theory and Application equips the reader with information about heat transfer problems occurring during phase changes. The book covers several boundary element methods, including methods for phase changes, fixed and moving domains and new approaches. The contents are rounded off with chapters on numerical results and industrial applications.

Key features:

- Simple, didactic presentation of boundary layer problems for heat transfer problems

- Covers a wide range of boundary element methods

- Includes methods for fixed and moving domains

- Explains industrial applications of the methods

- Includes solutions to numerical problems

The book serves as a textbook for students of advanced mathematics and engineering. It is also a handbook for researchers working on numerical analysis, who require a focused volume on boundary element methods for heat transfer applications.

Brain Tumour Drug Development provides a clear, multidisciplinary update on modern therapies for glioblastoma and other aggressive brain tumours. The book focuses on improving drug precision, crossing the blood-brain barrier, identifying biomarkers, designing effective trials, and accelerating translation from research to real patient care.

Key Features

Overcomes the blood-brain barrier using advanced delivery methods

Improves drug penetration & specificity with nano and polymer-based systems

Explores new therapies through immunotherapy, gene therapy, and personalised medicine

Builds preclinical models & identifies biomarkers to support clinical success

Designs regulatory-aligned clinical trial strategies for faster translation

Brain Tumor Targeting Drug Delivery Systems: Advanced Nanoscience for Theranostics Applications is a comprehensive reference focused on the latest advancements in nanotechnology for brain tumor therapy. With practical insights and cutting-edge research, this book equips readers with the knowledge to develop innovative drug delivery systems for effective brain tumor diagnosis and treatment. Structured into insightful chapters, this book covers the anatomy, physiology, and pathophysiology of the brain, addressing barriers to targeted drug delivery strategies. Chapters explore theranostics-based delivery systems, including polymeric nanoparticles, liposomes, dendrimers, nanoemulsions, micelles, and inorganic nanoparticles, for precise brain tumor diagnosis and treatment. This informative resource is designed for students and research scholars in pharmacology, pharmaceutical industry scientists, professors, and clinical medicine researchers. With comprehensive chapters and references for further reading, this book facilitates easy understanding of the intricate nanomedical technology, empowering researchers to make significant strides in the field of brain tumor therapy. Key Features: - Structured chapters for easy understanding of nanotechnology concepts - In-depth coverage of theranostics-based delivery systems for brain tumor diagnosis and treatment - References for further reading and exploring new advances in drug delivery systems

Breast cancer is one of the most common cancer types worldwide, and is a leading cause of cancer related deaths in women. In this book, medical experts review our current understanding of the molecular biology and characteristics of breast cancer. The topics covered in this book provide comprehensive knowledge of mechanisms underlying breast carcinogenesis, and are intended for a wide audience including scientists, teachers, and students.

11 chapters present information about several topics on breast cancer, including the role of cell growth and proliferation pathways, androgen and cytokine signaling, germline mutations in breast cancer susceptibility genes, and molecular factors causing invasive and metastatic breast cancer. In addition, the editors discuss the recent advancements in multi-omics data analysis based on inter-and intra-tumor molecular profiles.

The reference highlights how the knowledge and understanding of the biological behavior of breast neoplasms have facilitated ongoing investigations into dietary polyphenolic compounds with antioxidant properties, making them function as cancer chemopreventive agents. Along with this, the current development of treatment strategies such as targeted molecular therapy, and radiation therapy is brought to the fore to update readers.

Budget Optimization and Allocation: An Evolutionary Computing Based Model is a guide for computer programmers for writing algorithms for efficient and effective budgeting. It provides a balance of theory and practice. Chapters explain evolutionary computational techniques (genetic algorithms) and compare these techniques with traditional approaches to budget allocation.

A case study on the complex and broad problem of union budgeting of India is presented. The macro and micro economic issues specific to the case discussed, with the growth rate being the final aim of the budget exercise. The authors also present a comparison of the budget allocation practices of different countries, consistent with other factors such as their local economy, culture, population, etc. The use of evolutionary computation to tackle incremental budgeting is also presented. Readers will be able to understand the synergies of modern computational techniques with tried and tested budgeting models.

Budget Optimization and Allocation: An Evolutionary Computing Based Model is a useful reference for graduate students, business enterprise programmers, and evolutionary computing/AI researchers who seek to understand new methods of budgeting.

Business Models and Innovative Technologies for SMEs focuses on technologies such as data analytics, artificial intelligence and data as a service. As these technologies offer new possibilities, small and medium enterprises (SMEs) often struggle to grasp their full potential within evolving business landscapes. Five reviews discuss the potential of these technologies to drive SME growth. The book also highlights the need for a strategic approach to overcoming challenges faced by SMEs to create innovative business models such as limited resources, infrastructure hurdles, and financial limitations.

The chapters explore diverse facets of business model innovation, covering strategic models for mobile application development, the critical role of cybersecurity culture, readiness assessments, digital transformations leveraging artificial intelligence, expert systems' impact on competitiveness, and the adoption of data as services in SMEs. Each chapter is tailored to provide actionable insights drawn from theory and, where possible, real-life case studies, addressing questions related to technological benefits, innovative strategies, and challenges in implementing digital transformations for SMEs.

This book caters to a wide audience of academics, researchers, policymakers, and business practitioners deeply invested in SME development, offering practical solutions and theoretical frameworks. The combination of scholarly and practical approaches towards developing and implementing innovative strategies, makes it a valuable resource for readers seeking to understand and support SME growth.

In the battle against the COVID-19 pandemic, the integration of Internet of Things (IoT) technologies has played a pivotal role in reshaping public health and healthcare delivery. Interconnected devices have demonstrated their capacity to collect, transmit, and analyze data, significantly impacting various aspects of pandemic management. COVID-19 Monitoring with IoT Devices is a comprehensive guide to measuring the impact of COVID-19 infection and monitoring outbreak metrics. Beginning with an introduction to SARS-CoV-2 and its symptoms, the book presents chapters on machine learning (supervised and unsupervised algorithms) and techniques to predict COVID-19 outcomes. The book concludes with the role of IoT technology in detecting COVID-19 infections within a community, showcasing different computing models applicable to specific use-cases. Key Features: Explores the pivotal role of IoT technology in the fight against the COVID-19 pandemic. Covers a data-driven approach to COVID-19 monitoring by explaining methods for data collection, prediction, and analysis. Includes specific recommendations for machine learning algorithms designed for COVID-19 monitoring. Easy-to-read structured chapters suitable for novices in computer science and biomedical engineering. COVID-19 Monitoring with IoT Devices provides a valuable resource for understanding the role of IoT technology in managing and mitigating the impact of COVID-19, and developing adequate infection control policies. It also showcases the potential of IoT for future research and applications in the healthcare sector. This book is intended for a diverse readership, including academicians, industry professionals, researchers, and healthcare practitioners.

COVID-19: Causes, Transmission, Diagnosis, and Treatment is a simple guide to COVID-19 for all readers to give a thorough perspective about the disease. It comprehensively covers information about SARS-CoV-2 biology, clinical treatment and associated problems. It starts with key introductory topics such as COVID-19 epidemiology and viral biology. Next, it covers basic COVID-19 treatments and the impact of the disease in public health and economies. The book concludes by providing information on advanced technologies for COVID-19 radiograph imaging with AI and other machine learning techniques. Overall, content equips readers with a basic understanding about COVID-19 and the role of new technologies in overcoming challenges posed by the viral pandemic.

Key Features

- An accessible resource on COVID-19 for all readers

- Introduces the reader to SARS-CoV-2 variants, transmission routes and replication

- Explains COVID-19 symptoms and treatment methods

- Covers a diverse range of issues surrounding the COVID-19 pandemic

- Highlights key risks and challenges associated with COVID-19

- Covers current and emerging computer technologies that are useful for COVID-19 infection control

- Includes references for advanced readers

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings.

This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.

Key Features:

Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students.

Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19.

Six chapters in the first part which focus on clinical basics of COVID-19.

Six chapters in the second part which cover broader topics for practical infection control.

Multiple tables and figures which summarize and highlight important points.

Presents a summary of the current standards for the evaluation and diagnosis of COVID-19.

Features a detailed list of references, abbreviations, and symbols.

This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

COVID-19: Epidemiology, Biochemistry, and Diagnostics explains COVID-19 from multidisciplinary angles such as the evolution of SARS-COV, genetic techniques to study the virus, and diagnostic methodologies widely used in the global COVID-19 pandemic.

The chapters in this book provide the reader with up-to-date literature about research on SARS-CoV-2 through three parts:

I) Evolution and Entry of SARS-CoV-2 into the host

II) Genetic Alteration and Structural Determination of SARS-CoV-2 Proteins

III) Quantitative Analysis of SARS-CoV-2 for research and medical diagnosis

Key Features:

- 15 chapters on SAR-CoV-2 in a multidisciplinary context

- Provides a comprehensive overview of SARS-CoV-2 evolution and genetics

- Provides biochemical information about SARS-CoV-2 proteins and receptor targets (both structural and non-structural proteins)

- Includes an overview of several methods of detecting SARS-CoV-2 virus particles (ELISA, PCR, Neutralizing Antibodies

- Covers some critical diagnostic modalities for COVID-19 diagnosis

- Provides bibliographic references for further reading

Readers will understand the significance of phylogenetic analysis of coronaviruses, along with the pathogenesis of COVID-19 and related diseases such as SARS and MERS. Applications of biochemical technologies such as RT-PCR and CRISPR are also demonstrated in the text. This book is a comprehensive introduction to COVID-19 research for medical researchers, microbiologists and virologists. Students in academic programs in life sciences and medicine will also benefit from the information provided in the book.

COVID-19 has spread like wildfire across the globe since the start of the SARS-CoV-2 outbreak, hampering quality of life at multiple levels and causing many deaths. Many aspects of the human experience have been affected, with a body of research being published on its effects on psychological and physical well being, loss of jobs, pay cuts, education, and unpaid caregiving. New findings on these aspects are still emerging as we learn more about the consequences of the pandemic.

This book is intended as a simple summary of recent findings about COVID-19 for academicians and students from science, humanities and commerce backgrounds to understand the pandemic from a microscopic view and how it has touched our lives at different levels.

A collection of topics is presented and explored through chapters dedicated to niche topics on COVID-19. Each chapter is authored by expert scientists, academicians and scholars from leading institutions in India.

The key features of this book set are:

- Interdisciplinary content, making it useful for readers from different academic streams

- A blend of basic and applied research in biology, medicine and social science

- A focus on findings from India

- Updated References for advanced readers

This collection of topics is invaluable for researchers and working professionals in industry and academia as well as general readers who want a broad, insightful perspective on COVID-19.

Understanding Calculus as a Logical Extension of Arithmetic re-examines the calculus paradigm by expanding the set of ‘indeterminate forms’ espoused by l’Hôpital 320 years ago. Starting from the 54 possible binary combinations of the foundational numbers (zero, one and infinity), a replacement for the function theory formulated earlier by Newton and Leibniz, is presented. A logical extension of the three concepts of differentiation, integration and the Naperian base number e follows this introduction, which is interpreted as ‘zero divided by zero’, ‘infinity times zero’ and ‘one raised to the infinite power’, respectively. The concept that a number postulated as representing ‘nothing’ is reinforced a useful connection to calculus theory. This treatise proposes a ‘similar’ number to denote and quantify ‘all’, in order to understand the concept of infinity. Other topics covered in this text include analytical geometry, infinite sequences and infinite series.

Understanding Calculus as a Logical Extension of Arithmetic is a useful reference on advanced calculus theory for mathematics students and researchers.

Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease.

The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes 13-23 (volume 2). A key features of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.

Cancer Medicine in an Ayurvedic Perspective: A Critical Overview is a quick guide written to assist practitioners and Ayurveda academicians in understanding Ayurvedic views on cancer. This book is divided into nine chapters. It starts with a brief overview of cancer and epigenetics before delving into Ayurvedic approach to cancer etiopathogenesis, prevention and therapy. Concepts such as prakriti, Dincharya, Rutucharya and Yoga are explained alongside cancer screening and herbal medications. Whether you are a student of Ayurveda, working professional in medicine, a caregiver, or a general reader interested in the subject, this quick guide will give you a better understanding of how Ayurvedic medicine can be used to aid cancer patients.

Cancer is a major cause of deaths all around the globe. Although numerous anticancer drugs are available, most of them are expensive and have serious side effects. Natural compounds are usually non-toxic and inexpensive. Many such compounds have been identified and explored for their health benefits for centuries, and several nutritional factors derived from natural products have attracted considerable attention as therapeutic agents for the prevention and treatment of cancer. Based on current available research, this ebook focuses on chemopreventive and anti-cancer activities of different natural/dietary compounds present in fruits, vegetable, spices, legumes, nuts, grains, and cereals. Contributions from authors around the world highlight the potential use of such derivatives against cancer treatment by presenting updated information of their biochemical mechanisms. Information in this book is intended for researchers, clinicians, patients, academicians, industrialists, and students seeking updated and critical information for their experimental plans (including clinical trials). The book also creates awareness among cancer patients, nutritionists and laymen about cost effective therapeutic alternatives available for cancer therapy.

“Capitalist Realism” in Africa: Realities and Myths in Advertising is a multifaceted analysis of the role of advertising in the national development of Nigeria, and by extension, other African Nations. The book examines the unique political, cultural and religious systems that create the context for advertising in African countries and describes the unique historical, social, economic, communication and political context within which the practice of advertising takes place.  Since the end of the Cold War, the several African nations (or "emerging countries") have undertaken concrete efforts to reform their political, social, and economic institutions as they strive to join the global economy and improve the socioeconomic conditions of their citizens. To achieve these goals, administrators have relied on various forms of mass media – including advertising – to promote these reforms and socioeconomic development. Despite some unique challenges and opportunities as well as controversies surrounding the role of advertising in developing economies, advertising literature relevant to African countries remains in a blind spot. “Capitalist Realism” in Africa: Realities and Myths in Advertising bridges this gap by offering an in-depth analysis of advertising in an area of the world that has been largely neglected and provides a ground for generating a discussion about the practice of advertising in an African context.                                        

Cardiac Care and COVID-19: Perspectives in Medical Practice is an accessible reference on diagnoses and treatment modalities for cardiac diseases in general, and emergency cardiac conditions to be more specific, with respect to the current COVID-19 pandemic. Chapters in the book give updated descriptions of common problems in emergency medicine and cardiovascular disease. Each chapter is dedicated to a specific cardiovascular disease and explains management principles, diagnostic procedures and therapy. Examples of medical cases have also been used to highlight complex issues to give a concrete understanding of the cardiac care in COVID-19 patients to the medical practitioner, whether they are involved in critical care or in outpatient clinics.

Key Features:

- Clinical guidelines for critical care and cardiovascular management of COVID-19 patients

- Topic-based information about cardiovascular diseases

- Covers a range of cardiovascular problems including myocarditis, arrhythmias, chest pain, acute coronary syndrome

- Information on pulmonary embolism and associated problems

- Reader friendly presentation

- Case-based examples for explaining concepts

The range of topics combined with the simple presentation make this an essential reference for healthcare workers in emergency medicine, cardiology and nursing. General physicians interested in the cardiovascular impact of COVID-19 will also benefit from the information provided in the book.

Herbal Medicine: Back to the Future compiles expert reviews on the application of herbal medicines (including Ayurveda, Chinese traditional medicines and alternative therapies) to treat different ailments. The book series demonstrates the use of sophisticated methods to understand traditional medicine, while providing readers a glimpse into the future of herbal medicine.

This volume presents reviews of traditional Chinese medicine and other nutritional therapies useful for treating cardiovascular diseases, including:

- cardiovascular benefits of the European Olive and bottle gourd

- a review of the cardiovascular benefits of Naoxintong

- herbal and micronutrient supplements for cardiovascular disease patients

- herbal remedies for atherosclerosis

- cardio-protective alkaloids

This volume is essential reading for all researchers in the field of natural product chemistry and pharmacology. Medical professionals involved in cardiovascular care who seek to improve their knowledge about herbal medicine and alternative therapies will also benefit from the contents of the volume.

This anthology of articles on causal inference and scientific paradigms in epidemiology covers several important topics including the search for causal explanations, the strengths and limitations of causal criteria, quantitative approaches for assessing causal relationships that are relevant to epidemiology and emerging paradigms in epidemiologic research. In order to provide historical context, an overview of philosophical and historical developments relevant to causal inference in epidemiology and public health is also provided. Several theoretical and applied aspects of causal inference are dealt with. The aim of this Ebook is not only to summarize important developments in causal inference in epidemiology but also to identify possible ways to enhance the search for causal explanations for diseases and injuries. Examples are provided from such fields as chronic disease epidemiology, Veterans health, and environmental epidemiology. A particular goal of the Ebook is to provide ideas for strengthening causal inference in epidemiology in the context of refined research paradigms. These topics are important because the results of epidemiologic studies contribute to generalizable knowledge by clarifying the causes of diseases, by combining epidemiologic data with information from other disciplines (for example, psychology and industrial hygiene), by evaluating the consistency of epidemiologic data with etiological hypotheses about causation, and by providing the basis for evaluating procedures for health promotion and prevention and public health practices.

Over the past several decades the incidence of autism spectrum disorders (ASD) has increased dramatically. The etiology of ASD remains an unsolved puzzle to scientists, physicians, pediatricians, psychiatrists, and pharmacologists. Our E-book will address what is presently known concerning the pathophysiology of ASD from a cellular and molecular perspective. Our explanation is based on the interaction between repetitive systemic immune stimulation with concomitant chronic brain activation of microglia, which leads to overstimulation of glutamate receptors and inflammatory cytokine receptors. Our E-book will explain, for the first time, the effects of immunoexcitotoxicity on the brain development, neurophysiology, and pathology. Our book will not only attempt to explain the finding in ASD, but will offer treatment proposals that address each of these mechanisms. It will also explain how previous, often successful treatment methods, may indeed operate through the immunoexcitotoxic mechanism.

Cerium is the most abundant metal of rare-earth elements. It can be used to make materials such as phosphors and alloys, that have applications in various applied fields (like electronics, magnetics and heterogeneous catalysis) and devices (like catalytic converters and gas mantles). Cerium-Based Materials: Synthesis, Properties and Applications presents detailed knowledge about cerium materials. Starting with the history of cerium-based materials, it gives an introduction to the synthesis of chemicals like cerium oxides and composites. This is followed by information about characterization of cerium nanoparticles and industrial applications of cerium-based materials, with a focus on catalysis, biomedical engineering and pharmaceutical chemistry. This book is an essential reference for researchers and chemical engineers who want a summary of cerium materials and its applications.

Ever since some stars were found to pulsate in the early 20th century, stellar pulsation has been a major topic in astronomy and astrophysics. The huge amount of data recently available from observational surveys, new discoveries from space missions and studies of pulsating stars in low-metallicity environments have opened new perspectives and challenges. Nevertheless, progress in finding the holy grail of stellar pulsation – the use of pulsation to study stellar interiors (asteroseismology) – has been slow. The realization that a problem exists with the current stellar opacities is a major setback. CURRENT CHALLENGES IN STELLAR PULSATION describes the search for solutions to these problems over the last few years. It summarizes recent research in all fields of stellar pulsation, providing valuable guidelines to both students and researchers in the field.

Age-related degeneration may be reduced or even eliminated, by positively challenging the human being, physically or cognitively, to up-regulate somatic repair functions. Exposure to meaningful information and a challenging environment act as hormetic stressors which, in the context of an increasingly technological setting, may invoke evolutionary mechanisms that lead to a persistent maintenance of homeostasis. Thus, there is a strong link between environmental factors and ongoing health, leading to an individual’s ability to continually adapt to age related challenges.

Challenging Ageing: The Anti-senescence Effects of Hormesis, Environmental Enrichment, and Information Exposure explains the role of hormesis in anti-aging processes followed by information on vitagenes, epigenetics, environmental enrichment and germlines. The monograph also brings newer concepts and theories to the fore, such as ‘environmental enrichment’ and ‘technoculture.’ Medical professionals and general readers, alike, will gain a a new perspective on the processes that counter aging processes in the human being.

This research book compiles concise reviews on business trends that drive innovation and competitive advantages. The book includes 15 referenced chapters covering topics in advertising, agriculture, digital marketing, human resource management, healthcare and sustainability. Chapters focus on the use of disruptive technologies such as virtual reality, artificial intelligence and Internet of Things that harness the power of big data and visualizations to provide a framework for insightful analytics. Readers will be able to understand the practical applications and implications of these technologies so that they can apply them to their businesses. Special topics of interest are highlighted, including industry 4.0, women empowerment for industry 5.0, sustainability models for achieving UN SDG 9, over the top media platforms, and more.

This interdisciplinary reference work presents a linked consideration, to the reader, of physical-

cultural (physicocultural) representations of headstones located in urban churchyards in England and Scotland. The geomorphology of landscapes relevant to these locations is explained with the help of detailed case studies from Oxford and Edinburgh. The integrated physicocultural approach addresses the conservation of the archaeological record and presents a cross-temporal perspective of landscape change – of the headstones as landforms in their landscape (as part of deathscapes). The physical record (of headstones) is examined in the context of both cultural representation and change. In this way, an integrated approach is employed that connects the physical (natural) and cultural (social) records kept by historians and archeologists over the years.

Changing Landscapes in Urban British Churchyards is of interest to geomorphologists, historians and scholars interested in understanding landscaping studies and cultural nuance of specific historical urban sites in England and Scotland.