Bentham Science Publishers

Precision Medicine and Human Health covers several aspects of precision medicine in 20 edited reviews by researchers and healthcare professionals. The breadth of information provided by the contributors aims to familiarize readers with basic and applied research in personalized therapy.

Starting with an overview of the subject and its relationship with epigenetics, the book progresses into advanced topics that explain its wider applications. The use of precision medicine in treating different diseases such as protein misfolding disorders, gut ulcers and their effect on the gut microbiome, cancer treatment (for hepatocellular carcinoma, breast cancer, and oral cancer), fibromyalgia, high altitude sickness, and multiple sclerosis is explained. The book also covers modern therapeutic techniques to administer personalized therapy, including epithelial-mesenchymal therapy (EMT), circadian clock modulation, and artificial intelligence and phytoconstituents. The next chapters cover advanced technologies that are crucial to precision medicine, such as nanomaterials and advanced drug delivery systems. A concluding chapter on the therapeutic use of tannins in precision medicine rounds up the contents.

Key Features:

- Features 20 focused chapters contributed by scientific experts

- Introduces readers to basic concepts in precision medicine

- Covers the application of precision medicine in treating different diseases

- Showcases several techniques used in experimental and clinical precision therapy

- Explains modern technologies in precision medicine

- Caters to a wide readership with introductions, structured headings, and references

This is an informative reference for healthcare professionals in clinics and hospitals and any scholar who wants to learn about basic and applied knowledge in precision medicine.

Prediction in Medicine: The Impact of Machine Learning on Healthcare explores the transformative power of advanced data analytics and machine learning in healthcare. This comprehensive guide covers predictive analysis, leveraging electronic health records (EHRs) and wearable devices to optimize patient care and healthcare planning. Key topics include disease diagnosis, risk assessment, and precision medicine advancements in cardiovascular health and hypertension management.

The book also addresses challenges in interpreting clinical data and navigating ethical considerations. It examines the role of AI in healthcare emergencies and infectious disease management, highlighting the integration of diverse data sources like medical imaging and genomic data. Prediction in Medicine is essential for students, researchers, healthcare professionals, and general readers interested in the future of healthcare and technological innovation.

Pregnancy Disorders and Perinatal Outcomes offers readers insights into knowledge related to maternal habits or disorders that could affect fetal development and lead to disability later in childhood and adulthood. It contains chapters on the role of placenta, hormones, stress, nutrition, diabetes, hypertension, in vitro fertilization, obesity, immune systems and epigenetics in pregnancy well-being and perinatal outcomes. This ebook integrates both fundamental and clinical medicine and well as molecular and cell biology. It is written in a multidisciplinary context and would be a handy reference to a wide spectrum of readers including students, clinicians (obstetricians, neonatologists, pediatricians) and basic scientists in gynecology.

This eBook is a review on the state-of-the-art knowledge on currently available premium intraocular lenses. The volume covers a variety of intraocular lenses including multifocal, accommodative, aspheric, and toric versions and special intraocular biodevices such as intraocular telescopes. Details regarding their features, indications, contraindications and clinical results are also discussed based on evidence based / peer reviewed data. This eBook serves as a brief reference for optometry professionals seeking updates about high quality lenses for eye patients.

This eBook has been written in an easy style to understand the way to establish full clarity of the two subjects, dealt in the text books, Part "A" - Professional Practice and Ethics, and Part "B" - Engineering Law and Professional Liability. It eases the tough and complicated language used in the two textbooks. The simplicity of the language utilized to prepare the answers to the questions of the previous Professional Practice Examinations, paves a way to follow and understand these two subjects easily. The eBook can be considered as an essential prerequisite to the two textbooks assigned to the PPE candidates. The PPE candidates should consider this book as a useful tool in order to prepare themselves for the Examination.

Liver cancer, cirrhosis and nonalcoholic fatty liver disease are observed predominately in men. Being male or female is believed to be an important human variable that affects health and liver disease throughout the life span. However, few works have been published on the biological mechanisms underlying gender specific differences in liver disease. Several mechanisms underlying sex-associated differences of progression of liver disease are demonstrated in this e-book based on biological factors as estrogen and hepatic iron stores. Readers will gain a better understanding of the pathogenesis of these sex-associated differences in liver disease and on how to design healthcare for liver disease more effectively for individuals belonging to both genders. The e-book should be a useful reference on gender specific medicine for counselors and clinicians as well as for patients with chronic liver disease.

Principles of Automation and Control is a concise textbook that explains the basics of robust automation and control strategies. It demonstrates the essentials for meeting consumer needs and ensuring cost-effective manufacturing processes without compromising product quality. With a focus on Industry 4.0, this book explores the principles and applications of automation in industrial systems, emphasizing efficiency, profitability, and flexibility. The thirteen chapters cover automated processes, control theory, computer control devices, industrial automation tools, and practical examples of system automation. The text uses a multidisciplinary approach with simple language to cater to the needs of readers at all levels (learners, beginner engineers, and professionals) seeking to expand their knowledge in automation and control theory and practice. Real-world case studies and empirical findings are also highlighted, which show how automated business solutions can enhance performance.

This book provides notes for basic laboratory experiments in qualitative analysis of cations. The book introduces readers to basic methods and laboratory safety. Subsequent chapters cover six groups of cations. Each chapter explains important details that are required to understand how a particular analytical method works for detecting cations in samples, starting from sedimentation and ending with the identification.

Key Features:

- Simple, reader friendly format

- introductory notes and summary

- Covers several groups of metals

- Appendix for handy reference with tables and references

This is a useful textbook for early chemistry students and teachers as it equips the readers with sufficient information required to analyze chemical samples and deduce the presence of specific cations as part of laboratory coursework.

Probability and Statistics: Theory and Exercises is a textbook focused on practical examples of probability theory and statistics, with the goal of giving readers a thorough understanding of mathematical relationships in these subjects. The book is designed for basic courses in probability and statistics, and is aimed primarily at non-specialists and beginner level students.

The book is divided into 2 sections, respectively.

Probability: Includes a primer on set theory, basic probability theory definitions and calculations, combinatorial analysis, random variables and distribution laws

Statistics: Covers basic concepts of descriptive statistics

Key features

- Simple, clear language for easy comprehension of key concepts

- Carefully chosen exercises with solutions for self-learning

- Over 40 Illustrations for clear explanations

- References for further reading and tutorials.

Probiotics have been suggested to be involved in both prevention and treatment of various human cancers. Probiotics in Anticancer Immunity is a set of volumes in the Frontiers in Cancer Immunology series that explains biochemical mechanisms of anticancer immunity exerted by probiotics in various human cancers. It presents edited chapters focused on the evidence of probiotic use against human cancers through several animal and human studies.

This volume of Probiotics in Anticancer Immunity consists of 11 chapters. The introductory chapters provide information about the link between gut microbiota and the host immune system in cancer and the general mechanisms of anticancer immunity exerted by probiotics. Subsequent chapters are focused on probiotics' anticancer immunity in specific cancers such as, skin cancer, stomach cancer, breast cancer, lung cancer, head and neck cancer, liver cancer, cervical and colon cancer.

Key features

- Gives a new dimensions and insight in the role of probiotics in anticancer immunity towards various human cancers

- Provides several color figures and tables to clearly explain relevant information

- Includes recent information with new insights and references

- Meets the needs of basic (pre-clinical) and advanced clinical researchers and postgraduate scholars

Green economics refers to the discipline in which economists and businesses pursue policies that are conducive to minimizing environmental and ecological damage and therefore sustainable development.

Progress in Green Economics primarily focuses on developments in the transition of different industries and sectors to a sustainable, environment-friendly economic model. The book presents 7 chapters that cover different topics that reflect these developments in the field from a number of academic and practical angles.

The topics covered in the book include a review of the Food Energy Water Waste (FEWW) paradigm in Asian countries, an analysis of green economic forces in the Arctic region, green economics for protected area tourism, a conceptual analysis of green economics strategy, sustainable development and green banking in South Africa, and six sigma methodology for implementing green economic policies in different industries. Each chapter is organized into reader-friendly sections and is supplemented with references for the benefit of more involved scholars.

The multi-regional perspectives, along with the theoretical and practical information on the topic make this reference a timely and handy resource on green economics and sustainable development for academics, scholars, industrialists, policymakers and economics enthusiasts alike.

Promising Cancer Therapeutic Drug Targets: Recent Advancements offers a comprehensive overview of novel and emerging strategies in cancer therapy. The book explores cutting-edge approaches such as exosomal delivery systems, CRISPR/Cas9 gene editing, and immunotoxins, alongside targeting mechanisms like cancer stem cells, apoptosis pathways, and key signaling processes. A strong emphasis is placed on the therapeutic potential of natural compounds in disrupting cancer progression and enhancing treatment response. Chapters are organized around molecular targets, therapeutic pathways, and bioactive agents to provide a clear, thematic structure.

Key Features

- In-depth exploration of CRISPR/Cas9, exosomes, and stem cell-targeted therapy

- Focus on natural compounds in cancer treatment

- Insights into key signaling pathways (Hippo, Hedgehog, STAT3)

- Discussion on apoptosis and drug resistance mechanisms.

Neurodegenerative disorders such as Amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), Parkinson's disease (PD), Prion-related disorders (PrD) and Huntington's disease (HD) share a common neuropathology, primarily featuring the presence of abnormal protein inclusions containing specific misfolded proteins. These groups of diseases are now classified as Protein Misfolding Disorders. This Ebook gives a comprehensive overview of the possible mechanisms involved in Protein Misfolding Disorders and possible therapeutic strategies to treat these diseases. The Ebook provides the most recent evidence addressing the role of cellular stress responses to neurological diseases, along with therapeutic strategies to alleviate ER stress in a disease context.

Protocols used in Molecular Biology is a compilation of several examples of molecular biology protocols. Each example is presented with a concise introduction, materials and chemicals required, a step-by-step procedure and troubleshooting tips. Information about the application of the protocol is also provided. The techniques included in this book are essential to research in the fields of proteomics, genomics, cell culture, epigenetic modification and structural biology. The protocols can also be used by clinical researchers (neuroscientists and oncologists, for example) for medical applications (diagnostics, therapeutics and multidisciplinary projects).

In recent times, the phenomenon of lone wolf terrorism has been observed with the social assumption that a radicalized individual is only guided by personal, social, and ethnic reasons to commit an extremist act. Nevertheless, there is still much to understand about this phenomenon and improve the methods of investigation or psychiatric interventions. This handbook attempts to cover gaps in understanding the psychiatric aspects of radicalization and the phenomenon of lone-wolf terrorism. Edited by expert clinical psychologists, the contributors have taken both a qualitative and theoretical route to analyze the phenomenon, prompted by their clinical experience with mental health professionals, being in contact with radicalized people living in local towns and prisons.

Key Features

- Addresses the topic of lone wolf terrorism from multiple angles including psychological aspects, social aspects, philosophical aspects and prevention

- Provides insights into forensic psychiatric methods used to study terrorism

- Includes contributions from several mental health experts

- Explains information in a concise, easy to comprehend manner

- Includes references for further research

Psychological Assessment and Interventions for Individuals Linked to Radicalization and Lone Wolf Terrorism serves as a practical handbook for psychologists, psychiatrists, criminologists, social workers, allied professionals (such as law enforcement officers) and students (in criminology, social science or psychology programs for example) who want to learn about the causes and prevention of terrorism, with a focus on radicalization processes and lone wolf agents.

Demographic changes due to improved life expectancy and access to medical care has increased the number of people aged 65 years and beyond. This raises an important new challenge for healthcare professionals. Changes in organ functions, homeostatic mechanisms and receptor responsiveness impair drug distribution, metabolism and excretion, and reduce the effectiveness of medicines among geriatric patients. As a consequence, management of medical regimens is much more challenging in the elderly than in younger adult patients. Elderly patients are also more susceptible than other age groups to certain drug-drug interactions, drug-disease interactions and adverse drug reactions owing to the number of drugs administered.

Polypharmacy and potentially inappropriate medication is a common finding in the elderly healthcare and it is considered a public health issue related to morbidity, mortality and health care resource use.

Psychopharmacological Issues in Geriatrics can be regarded as a ‘pharmacovigilance’ manual for elderly patients as it presents recommendations for geriatric prescription with specific considerations.

The book also provides a comprehensive review of specific classes of psychopharmacological agents used to treat geriatric patients, including antipsychotics, anxiolytics, hypnotics and mood stabilizers. The book is intended as a handbook for general medical and nursing practitioners.

Quality Assurance of Ethno-Herbals: Cultivating Confidence in Alternative Medicine offers a comprehensive and scholarly examination of the essential methodologies, cultural considerations, and regulatory frameworks surrounding the quality assurance of ethno-herbal remedies. This volume bridges the rich legacy of traditional herbal practices with contemporary scientific inquiry, highlighting the critical need for rigorous validation, standardization, and ethical stewardship in the preservation and advancement of indigenous medicinal knowledge.

The book opens with an exploration of culinary heritage and the cultural significance of indigenous herbs, followed by a thoughtful analysis of the challenges inherent in preserving these valuable resources. It provides an in-depth discussion on the evolving role of Intellectual Property Rights (IPR) in the culinary and herbal domains, underscoring the importance of protecting traditional knowledge while promoting equitable access.

Through contributions from experts in ethnobotany, pharmacognosy, law, and cultural studies, the text examines collaborative models, policy frameworks, and future directions that aim to integrate ethno-herbal practices responsibly within modern healthcare systems. Emphasizing the ethical imperative of valuing and respecting indigenous wisdom, this volume serves as an authoritative resource for researchers, healthcare practitioners, policymakers, and academicians engaged in the fields of alternative medicine, herbal pharmacology, and cultural heritage preservation.

Queer and Subjugated Knowledges: Generating Subversive Imaginaries makes an invaluable contribution to gender and sexuality studies, engaging with queer theory to reconceptualize everyday interactions. The scholars in this book respond to J. Halberstam’s call to engage in alternative imaginings to reconceptualize forms of being, the production of knowledge, and envisage a world with different sites for justice and injustice. The recent work of cultural theorist, Judith Halberstam, makes new investments in the notion of the counter-hegemonic, the subversive and the alternative. For Halberstam, the alternative resides in a creative engagement with subjugated histories, an ecstatic investment in the subcultural and a defiant refusal of a dominant model of theory. Working across Rhetoric and Cultural Studies, Gender Studies, Performance Studies, Television and Media Studies, Animation, Sociology, History, Social Policy, Childhood Studies, Education, and Cultural Geography, this unique interdisciplinary text aimed at academics, undergraduate and postgraduate students provides challenging new frameworks for generating knowledge.

Bioinformatics allows researchers to answer biological questions with advanced computational methods which involves the application of statistics and mathematical modeling. Structural bioinformatics enables the prediction and analysis of 3D structures of macromolecules while Computer Aided Drug Designing (CADD) assists scientists to design effective active molecules against diseases. However, the concepts in structural bioinformatics and CADD can be complex to understand for students and educated laymen.

This quick guideline is intended as a basic manual for beginner students and instructors involved in bioinformatics and computational chemistry courses. Readers will learn the basics of structural bioinformatics, primary and secondary analysis and prediction, structural visualization, structural analysis and molecular docking. Therefore, the book is a useful handbook for aspiring scholars who wish to learn the basic concepts in computational analysis of biomolecules.

A multidisciplinary exploration of quinones as a vital structural class in medicinal chemistry Drawing from both natural and synthetic sources, the book explores the structural diversity, reactivity, and therapeutic potential of quinone compounds, positioning them as privileged moieties in the development of pharmacologically active agents.

The text covers essential themes such as synthesis strategies, identification techniques, biochemical relevance, and pharmacodynamics of quinones and their derivatives. It delves into their traditional use in medicine, contemporary roles in treating diseases like cancer and infections, and their capacity to interact with multiple biological targets. Specific chapters discuss glyco hybrids, ROS generation, enzymatic pathways, and toxicity profiles, offering a comprehensive overview of their medicinal versatility.

Key features:

Explores synthesis and structural modification techniques

Analyzes biochemical and pharmacodynamic mechanisms

Reviews traditional and modern therapeutic uses

Examines toxicity concerns and safety profiles

Highlights marketed drugs and emerging candidates

Presents recent studies and future trends.

This book details the development of techniques and ideas from the radial basis function. It begins with a mathematical description of the basic concept of radial function method with chapters progressively delving into the derivation and construction of radial basis functions for large-scale wave propagation problems including singularity problems, high-frequency wave problems and large-scale computation problems. This reference, written by experts in numerical analysis, demonstrates how the functions arise naturally in mathematical analyses of structures responding to external loads. Readers are also equipped with mathematical knowledge about the radial basis function for understanding key algorithms required for practical solutions.

Key features:

- Introduces basic concepts of radial basis function methods

- Provides detailed derivations of several radial basis functions

- Explains complex problems using simple language

- Contains a wide range of numerical examples to demonstrate applications of relevant functions

- Combines the radial basis function with other known numerical methods (boundary element methods and differential equations).

- Includes references and appropriate chapter appendices

- Includes MATLAB codes for origin intensity factors and nearly singular factors for radial basis calculations

The book is designed to make information about radial basis function methods more accessible to research scientists, professional engineers and postgraduate students, with a specific focus on large-scale wave propagation problems.

Rare Animals of India is a unique book that presents the biological and ecological accounts of the least known animal species of India in one comprehensive volume. The book gives comprehensive ecological accounts supported with data tables on rare and specific animal species of India and discusses the basis for their rarity for their conservation. It includes information about the Indian Gharial (Gavialis gangeticus) the endangered Forest Owlet (Heteroglaux blewitti), the Bengal Marsh Mongoose, Snow Leopards and many more. Readers are guided through several chapters each detailing a specific kind of animal, some of them being on the list of endangered species. With over 150 color illustrations, this intriguing reference will be of immense interest to zoologists, ecologists, naturalists and conservation biologists as well as general readers across the world interested in studying such rare or least known animals found in the length and breadth of the Indian region.

Recent Advancements in Computational Intelligence: Concepts, Methodologies and Applications (Part 1) is an in-depth exploration of computational intelligence (CI), a rapidly evolving field blending artificial intelligence, machine learning, and data-driven problem-solving. The book focuses on biologically inspired methods such as neural networks, fuzzy logic, swarm intelligence, and evolutionary algorithms; it showcases how CI addresses complex real-world problems marked by uncertainty and incomplete data. Integrating theory with Industry 4.0 applications, the book spans diverse domains including healthcare, autonomous systems, cybersecurity, and smart computing.

Structured across thematic sections like Social Computing, High-Performance Computing, Network Science, Smart Computing, and Intelligent Communications, it covers topics like deep learning for autonomous vehicles, AI-driven healthcare diagnostics, graph theory in cybersecurity, and reinforcement learning for generative AI. With contributions from international experts, it bridges foundational principles with applied research and case studies. Key Features:

• Integrates emerging trends such as generative AI, edge computing, and reinforcement learning.

• Demonstrates practical relevance through real-world case studies and industrial applications.

• Promotes interdisciplinary understanding across computer science, engineering, and healthcare.

• Provides actionable methodologies for researchers and practitioners advancing CI innovation.

• Highlights the fusion of theory and practice in intelligent, adaptive systems.

Heavy metal pollution represents a global challenge to both public health and environmental sustainability. Any means to reduce heavy metal pollution in the environment is of considerable economic significance. The use of green plants to clean up heavy metal pollution is an environmentally friendly as well as a low-cost approach to the problem. This plant-based biotechnology is commonly known as 'phytoremediation'. Presently, there is limited application of this technology because useful plants with enhanced heavy metal resistance/tolerance are still needed to assist remediation of environments polluted with heavy metals. A key to improved phytoremediation of heavy metal pollution lies in research seeking for a better understanding of the mechanism(s) of heavy metal resistance/tolerance in plants. This E-book presents a unique treatment of the topics that have never been comprehensively brought together before in a single advanced reference. The volume explores aspects of plant biology that are critical for employing phytoremedation techniques to combat heavy metal contamination such as the specific plant biology, seed biology, plant tissue culture and enzymology. This E-book will be a useful reference to plant biologists, biotechnologists and environmental engineers seeking information about phytoremediation of heavy metals from the environment.

Recent Advances in Analytical Techniques is a collection of updates in techniques used in chemical analysis. This volume presents information about a selection of analytical techniques. Readers will find information about:

- New methods of sample preparation in biological and environmental analysis

- Developments in electrochemical sensors

- In vivo cytometry for detection of tumor cells

- Flow discharge spectroscopy for depth profile analysis

- Advances in photodynamic therapy

- New methods to analyze volatility in alcoholic beverages