Bentham Science Publishers

RNA interference (RNAi) is a biological process in which small nucleotide sequences destroy specific mRNA molecules and, therefore, interrupt genetic expression. RNAi has rapidly developed into a widely used technique in biotechnology, experimental biology, genomics and medicine. Frontiers in RNAi is a collection of research articles covering the applications of RNAi principles and technologies and has been compiled by members of the RNAi Global Initiative, a collection of academic and industrial groups with extensive experience in genome-wide RNAi screening. Chapters included in the first volume touch on some of the recent advances in RNAi technology (i.e., applications to 3D cell culture, drug repurposing, and bioproduction) and provide guidance on how to address the continued challenges associated with off-target effects, database structuring, and pooled shRNA screens.

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics included in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 1 covers techniques for tissue engineering, wound healing and skin engineering. It also presents reviews on techniques such as acellular synthesis and 3D bioprinting. Materials highlighted in this part include chitosan-based nanoparticles, nanocollagen-based materials and plant based composites. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

The comprehensive information about the inverse relationship between the incidence of cancer and the consumption of natural food has impacted our understanding of the biochemical mechanisms behind cancer and its treatment. Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention is a review of pre-clinical studies unraveling the chemotherapeutic potential of phytochemicals and other food sources. The editors attempt to summarize the evidence, methods and techniques for identifying specific nutraceuticals and foods capable of interfering and reducing the risk of cancer.

The book compiles 19 edited chapters that cover the chemopreventive effects of different phytochemicals, animal and stem cell models for cancer prevention, and novel nanotechnology-based nutraceuticals. The contributors have also highlighted the techniques employed for the detection of cancer with a review on cancer biomarkers. The book is a resource for post-graduate students and researchers working in the field of nutrition, molecular biology, chemoprevention, biochemistry and pharmaceutical sciences.

Many beginners find physics to be a challenging subject to learn, and the difficulty extends to each branch of physics. It would be preferable for beginners to learn about different branches of physics as quickly as possible with a simplified understanding of the relevant mathematical relationships. After learning the position of each field in physics, it becomes easier to learn details of each field. In this book, special functions are not used to explain the solutions of equations.

Fundamentals of Analysis In Physics summarizes the analytical methods in different fields of physics The book covers several known fields of physics and is a useful text for beginners in physics, college and university students, and working professionals who may not have a background in mathematics or physics.

Key features:

- Summarizes information about different fields in physics in 150 pages

- Covers 7 different fields of physics (classical mechanics, electromagnetism, quantum mechanics, relativistic quantum mechanics, statistical mechanics and more) in 7 separate chapters

-Contains simple explanations without the use of special functions.

This textbook bridges the gap between introductory and advanced numerical methods for engineering students. The book initially introduces readers to numerical methods before progressing to linear and nonlinear equations. Next, the book covers the topics of interpolation, curve fitting and approximation, integration, differentiation and differential equations. The book concludes with a chapter on advanced mathematical analysis which explains methods for finite difference, method of moments and finite elements.

The book introduces readers to key concepts in engineering such as error analysis, algorithms, applied mathematics with the goal of giving an understanding of how to solve engineering problems using computational methods. Each of the featured topics is explained with sufficient detail while retaining the usual introductory nuance. This blend of beginner-friendly and applied information, along with reference listings makes the textbook useful to students of undergraduate and introductory graduate courses in mathematics and engineering.

Fundamentals of Materials Engineering - A Basic Guide is a helpful textbook for readers learning the basics of materials science. This book covers important topics and fundamental concepts of materials engineering including crystal structure, imperfections, mechanical properties of materials, polymers, powder metallurgy, corrosion and composites. The authors have explained the concepts in an effective way and by using simple language for the benefit of a broad range of readers. This book is also beneficial to the students in engineering courses at B.Sc, M.Sc, and M.Tech. levels.

Fundamentals of Nuclear Physics gives elementary understanding of nuclear and particle physics. The textbook offers an overview of the subject, providing students with a basic understanding about 1) the atomic structure and the nucleus, 2) equipment such as particle detectors, particle accelerators, and nuclear reactors, 3) radioactivity, and 4) elementary particles. Each chapter provides fundamental theoretical and experimental knowledge required for students to strengthen their concepts.

Other key features of the book include:

- Structured chapters designed for easy reading and stimulating interest for learners

- Sophisticated figures

- Thoroughly solved equations

- Bibliographic references for further reading

- Updated information about different types of nuclear reactors

- Information about nuclear astrophysics Fundamentals of Nuclear Physics is suitable for introductory undergraduate courses in nuclear physics as well as more innovative courses geared towards nuclear engineering.

Artificial Intelligence is playing a vital role in implementing the smart methods for the agriculture and it will change the aspects of performing agricultural activities. The objective of this book is to inform readers about how artificial intelligence is improving agriculture by exploring its applications. The book addresses several aspects of the artificial intelligence applications in the smart agriculture including, pest control, leaf disease identification, identification of weed, field security and applications of drones in smart farming. Chapters are contributed by experts in agriculture, computer science and biotechnology.

Key Themes:

Advanced machine learning techniques for pest control and disease identification

Automated recognition and classification of plant diseases, focusing on tomatoes and pearl millet

Integration of artificial intelligence for solar-powered robots to identify weeds and damages in vegetables

Development of field prevention systems to deter wild animals in farming areas

Utilization of machine learning for weather forecasting to facilitate smart agriculture practices

Intelligent crop planning and precision farming through AI applications

Integration of artificial intelligence and drones to enhance efficiency and effectiveness in smart farming operations

Other features of the book include a list of references and simple summaries in each chapter to distil the information for readers.

The book is a reference material for courses on automation in agriculture and as a handbook for anyone interested in new advances in farming.

This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria.

Key topics in part 2:

- Targeting pathogenic microbes for plants and animals using CRISPR-CAS

- Genome editing microbes to improve crop yield plant growth for sustainable agriculture

- Applications of genome editing for bioremediation

- Microbial genome editing for environmental bioprocessing

- Genetic engineering for methanotrophs

- Genome engineering in Cyanobacteria

- Genome editing in Streptomyces

Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics.

Geriatric Anesthesia: A Practical Guide is a comprehensive reference on geriatric anesthesia. The book is divided into three sections. The first section covers the basics of both anatomical and physiological changes in senescence, and important polypharmacy considerations common in elderly patients. The next section covers anesthesia for cardiac and non-surgical patients. Various controversies and legal ethical issues that are particularly significant in the elderly such as advance directives, code status discussions, specific patient groups and shared decision-making prior to surgical interventions, are covered in the final section.

Key features

- 20 referenced chapters covering basic geriatric anesthesia considerations, cardiac and non-surgical patients and special topics, respectively

- Contributions and references from experienced anesthesiologists

- Emphasis on tailoring perioperative management depending on specific circumstances of patients

- Addresses novel and commonly overlooked topics related to the geriatric population

This book is a guide for both anesthesia providers and non-anesthesia medical providers, trainees and students. It equips them with necessary information to understand and devise anesthetic plans while being aware of postoperative complications and the respective treatment and management options.