Bentham Science Publishers

Computer-Aided Drug Discovery Methods: A Brief Introduction explores the cutting-edge field at the intersection of computational science and medicinal chemistry. This comprehensive volume navigates from foundational concepts to advanced methodologies, illuminating how computational tools accelerate the discovery of new therapeutics.

Beginning with an overview of drug discovery principles, the book explains topics such as pharmacophore modeling, molecular dynamics simulations, and molecular docking. It discusses the application of density functional theory and the role of artificial intelligence in therapeutic development, showcasing successful case studies and innovations in COVID-19 research.

Ideal for undergraduate and graduate students, as well as researchers in academia and industry, this book serves as a vital resource in understanding the complex landscape of modern drug discovery. It emphasizes the synergy between computational methods and experimental validation, shaping the future of pharmaceutical sciences toward more effective and targeted therapies.

Conceptual Design of Green Transport Airplanes presents key information, methodologies, and modern tools for the conceptual design of airliners that comply with requirements to minimal environmental impact. The book is comprised of eight chapters that address relevant subjects such as airplane technological evolution, feasibility studies, design framework for conceptual design, and flight operations. Important issues and methods for an in-depth feasibility study are presented to facilitate the decision-making process of aircraft programs. These include examples of business plans for a 50-seat and 78-seat regional jets, description of design phases, market strategy, competition among manufacturers, regulatory requirements, and technology assessment.

Readers will also be introduced to modern methodologies used in the conceptual design process of transport airplanes, such as configuration study, aerodynamics, flight stability and control, performance, certification requirements and the role of flight operations. Thus, the design process is explained in an integrated manner which paves the way towards a better understanding of an optimized aeronautical design environment where noise and emission constraints are taken into consideration.

Conceptual Design of Green Transport Airplanes is an essential reference work for aeronautical engineering students and technicians as well as industry professionals involved in the aviation and environmental protection/regulation industry.

Coronaviruses publishes original research articles, letters, reviews/mini-reviews, clinical trial and guest edited thematic issues on all aspects of coronaviruses such as their origins, types, transmission, pathogenesis, epidemiological, demographic, clinical and genomic characteristics etc.

The Journal also covers case reports and studies on outbreak of coronaviruses, their symptoms, related diseases, prevention, treatment and development of new therapeutics.

In the last two decades, many new fractional operators have appeared, often defined using integrals with special functions in the kernel as well as their extended or multivariable forms. Modern operators in fractional calculus have different properties which are comparable to those of classical operators. These have been intensively studied for modelling and analysing real-world phenomena. There is now a growing body of research on new methods to understand natural occurrences and tackle different problems.

This book presents ten reviews of recent fractional operators split over three sections:

1. Chaotic Systems and Control (covers the Caputo fractional derivative, and a chaotic fractional-order financial system)

2. Heat Conduction (covers the Duhamel theorem for time-dependent source terms, and the Cattaneo Hristov model for oscillatory heat transfer)

3. Computational Methods and Their Illustrative Applications (covers mathematical analysis for understanding 5 real-word phenomena: HTLV-1 infection of CD4+ T-cells, traveling waves, rumor-spreading, biochemical reactions, and the computational fluid dynamics of a non-powered floating object navigating in an approach channel)

This volume is a resource for researchers in physics, biology, behavioral sciences, and mathematics who are interested in new applications of fractional calculus in the study of nonlinear phenomena.

Cultural Adaptation of Evidence-Based Psychotherapies for Common Mental Health Disorders in Pakistan offers a comprehensive overview of practical psychotherapy in a Pakistani cultural context. The authors aim to bridge knowledge gaps for practitioners who may be familiar with conventional methodologies and want to understand the subject from a regional perspective. The content includes seven meticulously written and referenced chapters that start with an overview of evidence-based therapy, progressing to modern psychotherapy techniques. The book concludes with information intended to guide the reader to adapt psychotherapy practices in Pakistani cultural settings.

Key Features

· Provides an introductory overview of evidence-based psychotherapy

· Provides an overview of psychotherapy practice in Pakistan

· Covers advanced technologies used in psychotherapy like Eye Movement Desensitization and Reprocessing, and Cognitive Behavioral Therapy to effectively address conditions such as post-traumatic stress disorder, depression, and anxiety

· Suggests culturally sensitive methodologies for practitioners working in Pakistani communities

This book is an ideal reference for clinical psychology researchers, psychotherapists, mental health counselors, academicians, and students. The insights in the book are invaluable, not only for Pakistani readers but also for those across Asia, providing a comprehensive blueprint for culturally adapting psychotherapies to diverse contexts.

Breast cancer is a recognized disease around the world with varying patient outcomes based on the type of breast cancer, access to healthcare and other factors. Survival rates for breast cancer are significantly lower in metastatic cases than localized cases. Early diagnosis and effective treatments for the efficient management of breast cancer are now in demand , as they help to prolong patient life. There have been many breakthrough developments in the molecular biology of breast cancer research in recent times. Advancements in diagnostic techniques (imaging and biomarker detection) for breast cancer have improved the screening of the disease and have improved patient outcomes. Despite these enhancements, the disease is still lethal for patients and the search for a cure requires a complete understanding of the disease.

Current Advances in Breast Cancer Research: A Molecular Approach presents a comprehensive overview of current basic and translational research on the subject. The 14 chapters of the book give emphasis to current knowledge about breast cancer, ongoing challenges, and innovative research findings by different research groups. Readers will find detailed information about breast cancer biology, genetics, clinical diagnostics and treatments. Additional information for advanced readers in life sciences, such as techniques relevant to genomics (including genetic fingerprinting), proteomics, metabolomics and medicine (such as imaging and molecular diagnostics) is also provided. The combination of both basic and advanced information makes this book a useful reference to the student and researcher, alike, seeking an understanding about breast cancer at a molecular level.

• Adhesion and Adhesive
• Aggregation-induced Emission Materials
• Alloys
• Biological Materials
• Biomaterials
• Ceramics
• Composites
• Dielectric Elastomers
• Electroactive Materials
• Fluorescent Materials
• Magnetic Materials
• Magneto-caloric and Magnetostrictive Materials
• Medical Implant Materials
• Metals and Metallurgy
• Nanomaterials
• Nanotechnology
• Nuclear Materials
• Ophthalmic Materials
• Polymeric Materials
• Shape Memory Alloys

• AI applications in medicine, law, and other disciplines
• Algorithms in artificial intelligence
• Artificial intelligence and philosophy
• Automated reasoning and inference
• Automatic control and robotics
• Bioinformatics
• Case-based reasoning
• Cognitive aspects of AI
• Common-sense reasoning
• Computing and the mind
• Constraint processing
• Heuristic search
• High-level computer vision
• Intelligent interfaces
• Intelligent robotics
• Machine learning
• Multiagent systems
• Natural computing
• Natural language processing
• Pervasive computing and ambient intelligence
• Planning and theories of action
• Reasoning under uncertainty or imprecision